ReviewTrends in molecular medicine2010
Placenta as a source of hematopoietic stem cells.
Review in Trends in molecular medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study.Frontiers of medicine · 2011Trial
- Ability to form Sox17-induced hematopoietic cell clusters varies among distinct hematopoietic sites during development.Inflammation and regeneration · 2026Article
- Dynamic Changes of Immunoreactive CD34, CD117, and CD41 Hematopoietic Stem Cells in Human Placentas of Different Gestational Ages.Journal of developmental biology · 2025Article
- Sox17 and Other SoxF-Family Proteins Play Key Roles in the Hematopoiesis of Mouse Embryos.Cells · 2024Review
- Prenatal alcohol exposure is associated with changes in placental gene co-expression networks.Scientific reports · 2024Article
- Placental cell conditioned media modifies hematopoietic stem cell transcriptome invitro.Placenta · 2024Article
- Linking Benzene, in Utero Carcinogenicity and Fetal Hematopoietic Stem Cell Niches: A Mechanistic Review.International journal of molecular sciences · 2023Review
- Multipotency of mouse trophoblast stem cells.Stem cell research & therapy · 2020Article
- A revised road map for the commitment of human cord blood CD34-negative hematopoietic stem cells.Nature communications · 2018Article
- Hypoxia and Placental Development.Birth defects research · 2017Review
- Fetal hemoglobin in umbilical cord blood in preeclamptic and normotensive pregnancies: A cross-sectional comparative study.PloS one · 2017Article
- Origin stories from a regional placenta tissue collection.New genetics and society · 2015Article
- Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this.Development (Cambridge, England) · 2014Article
- Transplantation of placenta-derived mesenchymal stem cells in the EAE mouse model of MS.Journal of molecular neuroscience : MN · 2012Article
- Perinatal sources of mesenchymal stem cells: Wharton's jelly, amnion and chorion.Cellular & molecular biology letters · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The placenta is a large, highly vascularised hematopoietic tissue that functions during the embryonic and foetal development of eutherian mammals. Although recognised as the interface tissue important in the exchange of oxygen, nutrients and waste products between the foetus and mother, the placenta has increasingly become a focus of research concerning the ontogeny of the blood system. Here, we describe recent data showing the intrinsic hematopoietic potential and appearance of hematopoietic cells in the mouse and human placenta and probe the biological rationale behind its hematopoietic function. As a rest tissue that contains potent hematopoietic stem cells (HSCs), the human placenta could represent (in addition to umbilical cord blood cells) an accessible supplemental source of cells for therapeutic strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.