Evidence map›Paper›PMID 20578718›Full record

ArticleEnvironmental science & technology2010

Predictors of serum dioxin, furan, and PCB concentrations among women from Chapaevsk, Russia.

Olivier Humblet, Paige L Williams, Susan A Korrick, Oleg Sergeyev, Claude Emond, Linda S Birnbaum, Jane S Burns, Larisa Altshul, Donald G Patterson, Wayman E Turner and 3 more

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Predictors of plasma polychlorinated biphenyl concentrations among reproductive-aged black women.International journal of hygiene and environmental health · 2019
    Article
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  8. Review
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  10. The spatial distribution of human exposure to PCBs around a former production site in Slovakia.Environmental science and pollution research international · 2015
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Olivier HumbletEnvironmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.
Paige L Williams
Susan A Korrick
Oleg Sergeyev
Claude Emond
Linda S Birnbaum
Jane S Burns
Larisa Altshul
Donald G Patterson
Wayman E Turner
Mary M Lee
Boris Revich
Russ Hauser
Brigham and Women's Hospital · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
PILOT AND FEASIBILITY PROGRAMP30DK032520 · NIDDK · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CZECH, MICHAEL P · 1986 to 2010
$14.6M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Effects of Environmental Phthalates and Chemical Mixtures on Male Puberty and Semen QualityR01ES014370 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI HAUSER, RUSS B · 2006 to 2021
$8.2M
Interdisciplinary Training in Genes and the EnvironmentT32ES016645 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI LEE, CHIH-HAO · 2008 to 2018
$4.0M
NIDDK NIH HHS P30 DK032520NIEHS NIH HHS 5T32-ES07069-28NIEHS NIH HHS ES00002NIEHS NIH HHS ES014370NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES014370NIEHS NIH HHS T32 ES007069NIEHS NIH HHS T32 ES016645
6 · The paper itself

Abstract

Dioxins, furans, and polychlorinated biphenyls (PCBs) are persistent and bioaccumulative toxic chemicals that are ubiquitous in the environment. We assessed predictors of their serum concentrations among women living in a Russian town contaminated by past industrial activity. Blood samples from 446 mothers aged 23-52 years were collected between 2003-2005 as part of the Russian Children's Study. Serum dioxin, furan, and PCB concentrations were quantified using high-resolution gas chromatography-mass spectrometry. Potential determinants of exposure were collected through interviews. Multivariate linear regression models were used to identify predictors of serum concentrations and toxic equivalencies (TEQs). The median total PCB concentrations and total TEQs were 260 ng/g lipid and 25 pg TEQ/g lipid, respectively. In multivariate analyses, both total PCB concentrations and total TEQs increased significantly with age, residential proximity to a local chemical plant, duration of local farming, and consumption of local beef. Both decreased with longer breastfeeding, recent increases in body mass index, and later blood draw date. These demographic and lifestyle predictors showed generally similar associations with the various measures of serum dioxins, furans, and PCBs.

Indexed as

AdultAgingDioxinsEnvironmental PollutantsFemaleFuransHumansMiddle AgedMultivariate AnalysisPolychlorinated BiphenylsRussiaYoung AdultDioxinsEnvironmental PollutantsFuransPolychlorinated Biphenyls

Identifiers

PMID20578718
PMCPMC3128795
OpenAlexW1992017109

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.