Evidence map›Paper›PMID 20577740›Full record

GuidelineEuropean journal of nuclear medicine and molecular imaging2010

Proposal for standardization of 123I-metaiodobenzylguanidine (MIBG) cardiac sympathetic imaging by the EANM Cardiovascular Committee and the European Council of Nuclear Cardiology.

Albert Flotats, Ignasi Carrió, Denis Agostini, Dominique Le Guludec, Claudio Marcassa, Michael Schäfers, Michael Schaffers, G Aernout Somsen, Mustafa Unlu, Hein J Verberne and 2 more

Erratum issuedAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in European journal of nuclear medicine and molecular imaging, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 157 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. The prognostic value ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Pooled it
  2. Update of the Brazilian Guideline on Nuclear Cardiology - 2020.Arquivos brasileiros de cardiologia · 2020
    Guideline
  3. MIBG scintigraphy in differential diagnosis of Parkinsonism: a meta-analysis.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2012
    Pooled it
  4. Trial
  5. [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  6. 18F-fluorodeoxyglucose use after cardiac transplant: A comparative study of suppression of physiological myocardial uptake.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Trial
  7. Relationship of left ventricular global longitudinal strain with cardiac autonomic denervation as assessed byJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Trial
  8. 1-23I-MIBG thyroid uptake: Implications for MIBG imaging of the heart.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Trial
  9. An improved method for estimating the heart-to-mediastinum ratio from cardiac sympathetic nerve imaging with low-energy high-resolution collimators.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Trial
  10. Trial
  11. Article
  12. Article
  13. Article
  14. Quantitative evaluation ofAnnals of nuclear medicine · 2026
    Article
  15. Article
  16. Review
  17. [Diagnostics (Basel, Switzerland) · 2025
    Article
  18. Establishment of aAnnals of nuclear medicine · 2025
    Article
  19. Review
  20. Value of multi-parameterEJNMMI research · 2025
    Article

97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
    Schaffers, Michael [corrected to Schäfers, Michael]
5 · Who and what money

Authors and funding

12 authors.

Albert FlotatsNuclear Medicine Department, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain. aflotats@santpau.cat
Ignasi Carrió
Denis Agostini
Dominique Le Guludec
Claudio Marcassa
Michael Schäfers
Michael Schaffers
G Aernout Somsen
Mustafa Unlu
Hein J Verberne
EANM Cardiovascular Committee
European Council of Nuclear Cardiology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This proposal for standardization of (123)I-metaiodobenzylguanidine (iobenguane, MIBG) cardiac sympathetic imaging includes recommendations for patient information and preparation, radiopharmaceutical, injected activities and dosimetry, image acquisition, quality control, reconstruction methods, attenuation, scatter and collimator response compensation, data analysis and interpretation, reports, and image display. The recommendations are based on evidence coming from original or scientific studies whenever possible and as far as possible reflect the current state-of-the-art in cardiac MIBG imaging. The recommendations are designed to assist in the practice of performing, interpreting and reporting cardiac sympathetic imaging. The proposed standardization does not include clinical indications, benefits or drawbacks of cardiac sympathetic imaging, and does not address cost benefits or cost effectiveness; however, clinical settings of potential utility are mentioned. Standardization of MIBG cardiac sympathetic imaging should contribute to increasing its clinical applicability and integration into current nuclear cardiology practice.

Indexed as

3-IodobenzylguanidineCardiologyContraindicationsDiagnostic ImagingEnvironmental ExposureEuropeHeartHumansImage Interpretation, Computer-AssistedNuclear MedicineQuality ControlRadiometryResearch DesignScattering, RadiationStatistics as TopicSympathetic Nervous System3-Iodobenzylguanidine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.