ArticlePMC biophysics2010
Bistability in the actin cortex.
Article in PMC biophysics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles.Nature communications · 2017Article
- Different modes of state transitions determine pattern in the Phosphatidylinositide-Actin system.BMC cell biology · 2011Article
- Curvature recognition and force generation in phagocytosis.BMC biology · 2010Article
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Authors and funding
1 author.
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Abstract
Multi-color fluorescence imaging experiments of wave forming Dictyostelium cells have revealed that actin waves separate two domains of the cell cortex that differ in their actin structure and phosphoinositide composition. We propose a bistable model of actin dynamics to account for these experimental observation. The model is based on the simplifying assumption that the actin cytoskeleton is composed of two distinct network types, a dendritic and a bundled network. The two structurally different states that were observed in experiments correspond to the stable fixed points in the bistable regime of this model. Each fixed point is dominated by one of the two network types. The experimentally observed actin waves can be considered as trigger waves that propagate transitions between the two stable fixed points.PACS Codes: 87.16.Ln, 87.17.Aa, 89.75.Fb.
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Registered trials
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