ArticleNano letters2010
Immobilization and one-dimensional arrangement of virus capsids with nanoscale precision using DNA origami.
Article in Nano letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 130 citations in OpenAlex.
- SynBioNanoDesign: pioneering targeted drug delivery with engineered nanomaterials.Journal of nanobiotechnology · 2025Review
- Label-free (fluorescence-free) sensing of a single DNA molecule on DNA origami using a plasmon-enhanced WGM sensor.Nanophotonics (Berlin, Germany) · 2025Article
- Analysis of DNA Origami Nanostructures Using Capillary Electrophoresis.Analytical chemistry · 2023Article
- Preparation and Biological Properties of Oligonucleotide-Functionalized Virus-like Particles.Biomacromolecules · 2023Article
- Functionalizing DNA origami to investigate and interact with biological systems.Nature reviews. Materials · 2023Article
- Article
- Hybrid Nanoassemblies from Viruses and DNA Nanostructures.Nanomaterials (Basel, Switzerland) · 2021Review
- Photocontrolled Dopamine Polymerization on DNA Origami with Nanometer Resolution.Angewandte Chemie (International ed. in English) · 2020Article
- Visualization of unstained homo/heterogeneous DNA nanostructures by low-voltage scanning transmission electron microscopy.Scientific reports · 2020Article
- Redox Engineering of Cytochrome c using DNA Nanostructure-Based Charged Encapsulation and Spatial Control.ACS applied materials & interfaces · 2019Article
- Precision engineering of targeted nanocarriers.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2018Review
- Beyond the smiley face: applications of structural DNA nanotechnology.Nano reviews & experiments · 2018Review
- Patterning protein complexes on DNA nanostructures using a GFP nanobody.Protein science : a publication of the Protein Society · 2016Article
- DNA Origami: Folded DNA-Nanodevices That Can Direct and Interpret Cell Behavior.Advanced materials (Deerfield Beach, Fla.) · 2016Review
- Journey to the Center of the Cell: Current Nanocarrier Design Strategies Targeting Biopharmaceuticals to the Cytoplasm and Nucleus.Current pharmaceutical design · 2016Review
- A Simple RNA-DNA Scaffold Templates the Assembly of Monofunctional Virus-Like Particles.Journal of the American Chemical Society · 2015Article
- High precision and high yield fabrication of dense nanoparticle arrays onto DNA origami at statistically independent binding sites.Nanoscale · 2014Article
- Formation mechanism of chalcogenide nanocrystals confined inside genetically engineered virus-like particles.Scientific reports · 2014Article
- Orthogonal labeling of M13 minor capsid proteins with DNA to self-assemble end-to-end multiphage structures.ACS synthetic biology · 2013Article
- Location of the bacteriophage P22 coat protein C-terminus provides opportunities for the design of capsid-based materials.Biomacromolecules · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
DNA origami was used as a scaffold to arrange spherical virus capsids into one-dimensional arrays with precise nanoscale positioning. To do this, we first modified the interior surface of bacteriophage MS2 capsids with fluorescent dyes as a model cargo. An unnatural amino acid on the external surface was then coupled to DNA strands that were complementary to those extending from origami tiles. Two different geometries of DNA tiles (rectangular and triangular) were used. The capsids associated with tiles of both geometries with virtually 100% efficiency under mild annealing conditions, and the location of capsid immobilization on the tile could be controlled by the position of the probe strands. The rectangular tiles and capsids could then be arranged into one-dimensional arrays by adding DNA strands linking the corners of the tiles. The resulting structures consisted of multiple capsids with even spacing (approximately 100 nm). We also used a second set of tiles that had probe strands at both ends, resulting in a one-dimensional array of alternating capsids and tiles. This hierarchical self-assembly allows us to position the virus particles with unprecedented control and allows the future construction of integrated multicomponent systems from biological scaffolds using the power of rationally engineered DNA nanostructures.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.