Evidence map›Paper›PMID 20574807›Full record

ReviewJournal of molecular medicine (Berlin, Germany)2010

Complex role of the HIF system in cardiovascular biology.

Gabor Czibik

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular medicine (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Qianyang Yuyin granule modulates glycolysis and inflammatory response to treat hypertensive cardiac remodeling.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Article
  2. Article
  3. Review
  4. Acute Methylmercury Exposure and the Hypoxia-InducibleEnvironmental health perspectives · 2019
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gabor CzibikDepartment of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, West Wing, Level 6, Headley way, OX3 9DU, Oxford, UK. gabor.czibik@cardiov.ox.ac.uk

Funding

British Heart Foundation
6 · The paper itself

Abstract

The hypoxia-inducible factor (HIF) system was discovered as an oxygen-sensitive regulatory pathway that confers adaptive responses to hypoxia. Novel aspects of this growing network indicate that there is a significant, nonhypoxic contribution to regulation. Multiple lines of evidence suggest that components of the HIF pathway are intimately involved in the pathogenesis of cardiovascular disorders. This review highlights the functional context of the HIF system in cardiovascular pathobiology with possible therapeutic implications.

Indexed as

Cardiovascular Physiological PhenomenaAnimalsCardiovascular DiseasesHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitOxygenProcollagen-Proline DioxygenaseProtein IsoformsHypoxia-Inducible Factor 1, alpha SubunitOxygenProcollagen-Proline DioxygenaseProtein Isoforms

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.