Trial reportEuropean journal of applied physiology2010
The influence of menthol on thermoregulation and perception during exercise in warm, humid conditions.
Trial report in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of internal cooling on physical performance, physiological and perceptional parameters when exercising in the heat: A systematic review with meta-analyses.Frontiers in physiology · 2023Pooled it
- Menthol can be safely applied to improve thermal perception during physical exercise: a meta-analysis of randomized controlled trials.Scientific reports · 2020Pooled it
- Effects of Menthol Mouth Rinsing on Performance and Surface EMG Activity During Heat-Stressed Cycling.Nutrients · 2026Trial
- Menthol Mouth Rinsing Maintains Relative Power Production during Three-Minute Maximal Cycling Performance in the Heat Compared to Cold Water and Placebo Rinsing.International journal of environmental research and public health · 2022Trial
- Effects of a cooling vest with sham condition on walking capacity in heat-sensitive people with Multiple Sclerosis.European journal of applied physiology · 2020Trial
- L-Menthol attenuates the magnitude of cold-induced vasodilation on the extremities of young females.Journal of physiological anthropology · 2018Trial
- Oral L-menthol reduces thermal sensation, increases work-rate and extends time to exhaustion, in the heat at a fixed rating of perceived exertion.European journal of applied physiology · 2017Trial
- Physical and perceptual cooling with beverages to increase cycle performance in a tropical climate.PloS one · 2014Trial
- Toward isolating perceptual and physiological contributors to heat sensitivity in multiple sclerosis: insights from a new experimental model.European journal of applied physiology · 2025Article
- Peripheral skin cooling during gravitational challenges in parabolic flight - experimental protocol, implementation, and case study of the CoolFly experiment.Frontiers in physiology · 2025Article
- Influence of topical menthol gel on thermoregulation and perception while walking in the heat.European journal of applied physiology · 2024Article
- Effects of 24 h Compression Interventions with Different Garments on Recovery Markers during Running.Life (Basel, Switzerland) · 2021Article
- Menthol as an Ergogenic Aid for the Tokyo 2021 Olympic Games: An Expert-Led Consensus Statement Using the Modified Delphi Method.Sports medicine (Auckland, N.Z.) · 2020Article
- Thermoregulatory and cardiovasculareffects of capsaicin application on human skin during dynamic exercise to temperate and warm conditions.Physiological reports · 2019Article
- Menthol as an Adjuvant to Help Athletes Cope With a Tropical Climate: Tracks From Heat Experiments With Special Focus on Guadeloupe Investigations.Frontiers in physiology · 2019Review
- Improvement of the pharmacological activity of menthol via enzymatic β-anomer-selective glycosylation.AMB Express · 2017Article
- Menthol: A Fresh Ergogenic Aid for Athletic Performance.Sports medicine (Auckland, N.Z.) · 2017Article
- Desensitization of menthol-activated cold receptors in lower extremities during local cooling in young women with a cold constitution.The journal of physiological sciences : JPS · 2017Article
- Effects of Intermittent Neck Cooling During Repeated Bouts of High-Intensity Exercise.Sports (Basel, Switzerland) · 2016Article
- Body regional influences of L-menthol application on the alleviation of heat strain while wearing firefighter's protective clothing.European journal of applied physiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Menthol has recently been added to various cooling products that claim to enhance athletic performance. This study assessed the effect of two such solutions during exercise in warm, humid conditions. Twelve participants (22 ± 2.9 years; VO2peak 47.4 ± 6.2 mL kg(-1) min(-1)) completed a peak power (PO(peak)) test and three separate exercise bouts in 30°C and 70% relative humidity after being sprayed with 100 mL of water containing either 0.05 or 0.2% l-menthol, or a control spray. During each trial, participants underwent 15 min of rest, spraying, 15 min of rest and 45 min of exercise at 45% of PO(peak). The following variables were measured: rectal temperature (T (re)), sweat rate (SR), skin blood flow (SBF), heart rate (HR), thermal comfort (TC) and sensation (TS) votes, irritation (IRR) and rating of perceived exertion (RPE). Mean skin (MST) and body temperatures (Tbody) were calculated. There was no significant difference in MST, Tbody SR, SBF, HR, TC or RPE between conditions. Spraying with 0.2% menthol significantly (P < 0.05) elevated T (re) by 0.2°C compared to the other conditions. Both menthol sprays caused participants to feel significantly cooler than control spraying (P = 0.001), but 0.2% spraying induced significantly cooler sensations (P = 0.01) than 0.05% spraying. Both menthol sprays induced greater irritation (P < 0.001) than control spraying. These findings suggest that 0.05% menthol spraying induced cooler upper body sensations without measurable thermoregulatory impairment. T (re) was significantly elevated with 0.2% spraying. Irritation persisted with both menthol sprays while TC remained unchanged, suggesting a causal relationship. The use in sport of a spray similar to those tested here remains equivocal.
Indexed as
Identifiers
20574677What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.