ArticleNeurology2010
Quality of life declines after first ischemic stroke. The Northern Manhattan Study.
Article in Neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Socioeconomic status and health-related quality of life after stroke: a systematic review and meta-analysis.Health and quality of life outcomes · 2023Pooled it
- Effect of ginkgo diterpene lactone meglumine on the quality of life in patients with acute ischemic stroke.Health and quality of life outcomes · 2024Trial
- Rehabilitation Transition Program to Improve Community Participation Among Stroke Survivors: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Recurrent stroke was associated with poor quality of life in patients with transient ischemic attack or minor stroke: finding from the CHANCE trial.CNS neuroscience & therapeutics · 2014 · on this mapTrial
- Quality of life after lacunar stroke: the Secondary Prevention of Small Subcortical Strokes study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke AssociationTrial
- Sex Differences in Outcomes Over the First Year After Ischemic Stroke: A Population-Based Longitudinal Study.Neurology · 2026Article
- Health literacy and urban-rural disparities: a cross-sectional study of access, adherence, and quality of life across the neurological spectrum.Frontiers in public health · 2026Article
- Balancing Rehabilitation Dose in Acute Stroke Decision-Making and Global Assessment (The BRIDGE Study).Journal of clinical medicine · 2025Article
- Remotely Supervised Transcranial Direct Current Stimulation in Post-Stroke Recovery: A Scoping Review.Medicina (Kaunas, Lithuania) · 2025Article
- Novel Robotic Balloon-Based Device for Wrist-Extension Therapy of Hemiparesis Stroke Patients.Sensors (Basel, Switzerland) · 2025Article
- Psychometric Properties of the Toileting Behaviour Evaluation (TBE) Using Rasch Analysis.Cureus · 2025Article
- Healthy life expectancy with cardiovascular disease among Chinese rural population based on the prospective cohort study.Journal of geriatric cardiology : JGC · 2024Article
- Availability of family care resources, bathing assistance and toileting assistance among older adults with functional limitations: an evidence-based study from China.BMC geriatrics · 2024Article
- Machine learning-based prediction of early neurological deterioration after intravenous thrombolysis for stroke: insights from a large multicenter study.Frontiers in neurology · 2024Article
- Development of toileting behaviour evaluation for Japanese older patients using wheelchairs in a hospital setting: a validation study.BMC geriatrics · 2023Article
- Cardiovascular risk reduction with integrated care: results of 8 years follow up.BMC primary care · 2023Article
- Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.Circulation · 2023Review
- Psychometrics and validation of the EQ-5D-5L instrument in individuals with ischemic stroke in Lithuania.Frontiers in psychology · 2023Article
- Association between small dense low-density lipoprotein cholesterol and neuroimaging markers of cerebral small vessel disease in middle-aged and elderly Chinese populations.BMC neurology · 2021Article
- Health-related quality of life after first-ever acute ischemic stroke: associations with cardiovascular health metrics.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
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7 authors.
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Abstract
objectivesQuality of life (QOL) after stroke is poorly characterized. We sought to determine long-term natural history and predictors of QOL among first ischemic stroke survivors without stroke recurrence or myocardial infarction (MI).
methodsIn the population-based, multiethnic Northern Manhattan Study, QOL was prospectively assessed at 6 months and annually for 5 years using the Spitzer QOL index (QLI), a 10-point scale. Functional status was assessed using the Barthel Index (BI) at regular intervals, and cognition using the Mini-Mental State Examination at 1 year. Generalized estimating equations estimated the association between patient characteristics and repeated QOL measures over 5 years. Follow-up was censored at death, recurrent stroke, or MI.
resultsThere were 525 incident ischemic stroke patients >/=40 years (mean age 68.6 +/- 12.4 years). QLI declined after stroke (annual change -0.10, 95% confidence interval -0.17 to -0.04), after adjusting for age, sex, race-ethnicity, education, insurance, depressed mood, stroke severity, bladder continence, and stroke laterality. This decline remained when BI >/=95 was added to the model as a time-dependent covariate, and functional status also predicted QLI. Changes in QLI over time differed by insurance status (p for interaction = 0.0017), with a decline for those with Medicaid/no insurance (p < 0.0001) but not Medicare/private insurance (p = 0.98).
conclusionsIn this population-based study, QOL declined annually up to 5 years after stroke among survivors free of recurrence or MI and independently of other risk factors. QLI declined more among Medicaid patients and was associated with age, mood, stroke severity, urinary incontinence, functional status, cognition, and stroke laterality.
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