Evidence map›Paper›PMID 20573547›Full record

ReviewCurrent opinion in pharmacology2010

Immunotherapy for allergies and asthma: present and future.

Shyam S Mohapatra, Momina Qazi, Gary Hellermann

Abstract readReview
In one paragraph

Review in Current opinion in pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Specific allergen immunotherapy for the treatment of atopic eczema.The Cochrane database of systematic reviews · 2016
    Pooled it
  2. Egg Allergy: Diagnosis and Immunotherapy.International journal of molecular sciences · 2020
    Review
  3. Mechanism(s) of prolonged attenuation of allergic responses after modulation of idiotypic regulatory network.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019
    Article
  4. Review
  5. Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis.International archives of otorhinolaryngology · 2016
    Article
  6. Novel challenges for the allergist.Clinical reviews in allergy & immunology · 2011
    Article
  7. Management of rhinitis: allergic and non-allergic.Allergy, asthma & immunology research · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shyam S MohapatraDepartment of Internal Medicine, Division of Allergy and Immunology, University of South Florida College of Medicine, Tampa, FL, USA. smohapat@health.usf.edu
Momina Qazi
Gary Hellermann
Florida College · USJames A. Haley Veterans' Hospital · US

Funding

Nanomedicine Research Center Core (NRCC)P30HL101265 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI MOHAPATRA, SHYAM S · 2009 to 2010
$1.3M
Association between ANP and NPRA Gene Polymorphisms and Severity of Atopy and AstR21HL088299 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI MOHAPATRA, SHYAM S · 2008 to 2009
$436k
NHLBI NIH HHS 1R21HL088299-01A2NHLBI NIH HHS P30 HL101265NHLBI NIH HHS R21 HL088299
6 · The paper itself

Abstract

Allergen immunotherapy (IT) is a proven approach for treating allergic rhinitis and allergic asthma that has been practiced since 1911 and has undergone significant development in the past two decades. As currently practiced, IT involves subcutaneous or sublingual administration of allergens, both methods of which have been extensively investigated. In addition to allergen IT, a number of additional nonspecific IT approaches are being used or are in phase II/phase III clinical trials, which may be available in clinics within the next one to three years. Such therapies include anti-IgE antibodies and the soluble IL-4 receptor. Other experimental IT approaches are at the preclinical research stage and may proceed to clinical trials and the clinic within the next five to ten years. This review discusses the pros and cons of recent developments in both currently practiced and experimental IT approaches.

Indexed as

AllergensAnimalsAsthmaClinical Trials as TopicHumansHypersensitivityImmunotherapyRhinitis, Allergic, PerennialRhinitis, Allergic, SeasonalAllergens

Identifiers

PMID20573547
PMCPMC2915930
OpenAlexW2010773995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.