SynthesisJournal of the International AIDS Society2010
Lessons learned from family-centred models of treatment for children living with HIV: current approaches and future directions.
Synthesis in Journal of the International AIDS Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Retention in care of HIV-infected children from HIV test to start of antiretroviral therapy: systematic review.PloS one · 2013Pooled it
- Trial
- Mother-child dyads living with HIV in the Western Cape, South Africa: Undetectable = Undetectable?Journal of the International AIDS Society · 2025Article
- Retention in care of infants diagnosed with HIV at birth: Beyond the diagnostic strategy.Southern African journal of infectious diseases · 2024Article
- Organisation of care for people receiving drug-resistant tuberculosis treatment in South Africa: a mixed methods study.BMJ open · 2023Article
- Article
- Outcome of HIV Testing Among Family Members of Index Cases Across 36 Facilities in Abidjan, Côte d'Ivoire.AIDS and behavior · 2021Article
- The Evolution of Dignity: An Intervention Model to Engage and Retain HIV-Positive Black Women in Care.Journal of healthcare, science and the humanities · 2021Article
- Psychosocial support interventions for improved adherence and retention in ART care for young people living with HIV (10-24 years): a scoping review.BMC public health · 2020Article
- 'There are no more secrets': acceptability of a family-centered model of care for HIV positive children in Eswatini.BMC health services research · 2020Article
- Discordant retention of HIV-infected mothers and children: Evidence for a family-based approach from Southern Mozambique.Medicine · 2020Observational
- Article
- How are children with HIV faring in Nigeria?--a 7 year retrospective study of children enrolled in HIV care.BMC pediatrics · 2015Article
- Family matters: Co-enrollment of family members into care is associated with improved outcomes for HIV-infected women initiating antiretroviral therapy.Journal of acquired immune deficiency syndromes (1999) · 2014Article
- Beyond prevention of mother-to-child transmission: keeping HIV-exposed and HIV-positive children healthy and alive.AIDS (London, England) · 2013Review
- Outcomes of antiretroviral therapy in children in Asia and Africa: a comparative analysis of the IeDEA pediatric multiregional collaboration.Journal of acquired immune deficiency syndromes (1999) · 2013Article
- Scaling up paediatric HIV care with an integrated, family-centred approach: an observational case study from Uganda.PloS one · 2013Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite strong global interest in family-centred HIV care models, no reviews exist that detail the current approaches to family-centred care and their impact on the health of children with HIV. A systematic review of family-centred HIV care programmes was conducted in order to describe both programme components and paediatric cohort characteristics.
methodsWe searched online databases, including PubMed and the International AIDS Society abstract database, using systematic criteria. Data were extracted regarding programme setting, staffing, services available and enrolment methods, as well as cohort demographics and paediatric outcomes.
resultsThe search yielded 25 publications and abstracts describing 22 separate cohorts. These contained between 43 and 657 children, and varied widely in terms of staffing, services provided, enrolment methods and cohort demographics. Data on clinical outcomes was limited, but generally positive. Excellent adherence, retention in care, and low mortality and/or loss to follow up were documented.
conclusionsThe family-centred model of care addresses many needs of infected patients and other household members. Major reported obstacles involved recruiting one or more types of family members into care, early diagnosis and treatment of infected children, preventing mortality during children's first six months of highly active antiretroviral therapy, and staffing and infrastructural limitations. Recommendations include: developing interventions to enrol hard-to-reach populations; identifying high-risk patients at treatment initiation and providing specialized care; and designing and implementing evidence-based care packages. Increased research on family-centred care, and better documentation of interventions and outcomes is also critical.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.