SynthesisWorld journal of gastroenterology2010
Evidence-based appraisal in laparoscopic Nissen and Toupet fundoplications for gastroesophageal reflux disease.
Synthesis in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Laparoscopic Nissen Versus Toupet Fundoplication for Short- and Long-Term Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis and Systematic Review.Surgical innovation · 2023Pooled it
- Surgical treatment of recalcitrant gastroesophageal reflux disease in patients with systemic sclerosis: a systematic review.Langenbeck's archives of surgery · 2021Pooled it
- A meta-analysis of long follow-up outcomes of laparoscopic Nissen (total) versus Toupet (270°) fundoplication for gastro-esophageal reflux disease based on randomized controlled trials in adults.BMC gastroenterology · 2016Pooled it
- Pooled it
- Influence of wrap length on the effectiveness of Nissen and Toupet fundoplications: 5-year results of prospective, randomized study.Surgical endoscopy · 2013Trial
- Endoscopic full-thickness plication versus laparoscopic fundoplication: a prospective study on quality of life and symptom control.Surgical endoscopy · 2012Trial
- A retrospective study assessing RefluxStop surgery for gastroesophageal reflux disease: Clinical outcomes in 79 patients from Germany.Surgery open science · 2025Article
- Laparoscopic Toupet fundoplication: a safe and effective anti-reflux option in lung transplant recipients.Surgical endoscopy · 2023Article
- Long-term outcomes following Dor, Toupet, and Nissen fundoplication: a network meta-analysis of randomized controlled trials.Surgical endoscopy · 2023Review
- Modelling Stakeholder Valuation: An Example Using the Surgical Treatments for Gastroesophageal Reflux Disease.Cureus · 2021Article
- Laparoscopic antireflux surgery: how I do it?Updates in surgery · 2018Article
- Surgical Treatment of Gastroesophageal Reflux Disease.World journal of surgery · 2017Review
- Backflow prevention mechanism of laparoscopic Toupet fundoplication using high-resolution manometry.Surgical endoscopy · 2016Article
- Laparoscopic surgery: A qualified systematic review.World journal of methodology · 2015Article
- Comparison of Stretta procedure and toupet fundoplication for gastroesophageal reflux disease-related extra-esophageal symptoms.World journal of gastroenterology · 2015Article
- Evaluation of short-term and long-term results after laparoscopic antireflux surgery: esophageal manometry and 24-h pH monitoring versus quality of life index.Langenbeck's archives of surgery · 2013Article
- Review on novel concepts of columnar lined esophagus.Wiener klinische Wochenschrift · 2013Review
- New Ovine Polymer-Reinforced Bioscaffold in Hiatal Hernia Repair.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo demonstrate the optimal surgical procedure for gastroesophageal reflux disease.
methodsThe electronic databases of Medline, Elsevier, Springerlink and Embase over the last 16 years were searched. All clinical trials involved in the outcomes of laparoscopic Nissen fundoplication (LNF) and laparoscopic Toupet fundoplication (LTF) were identified. The data of assessment in benefits and adverse results of LNF and LTF were extracted and compared using meta-analysis.
resultsWe ultimately identified a total of 32 references reporting nine randomized controlled trials, eight prospective cohort trials and 15 retrospective trials. These studies reported a total of 6236 patients, of whom 4252 (68.18%) underwent LNF and 1984 (31.82%) underwent LTF. There were no differences between LNF and LTF in patients' satisfaction, perioperative complications, postoperative heartburn, reflux recurrence and re-operation. Both LNF and LTF enhanced the function of lower esophageal sphincter and improved esophagitis. The postoperative dysphagia, gas-bloating syndrome, inability to belch and the need for dilatation after LNF were more common than after LTF. Subgroup analyses showed that dysphagia after LNF and LTF was similar in patients with normal esophageal peristalsis (EP), but occurred more frequently in patients with weak EP after LNF than after LTF. Furthermore, patients with normal EP after LNF still had a higher risk of developing dysphagia than did patients with abnormal EP after LTF.
conclusionCompared with LNF, LTF offers equivalent symptom relief and reduces adverse results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.