Trial reportEuropean radiology2010
Comparison of standard- and low-tube voltage MDCT angiography in patients with peripheral arterial disease.
Trial report in European radiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Trial
- Low-dose CT angiography using ASiR-V for potential living renal donors: a prospective analysis of image quality and diagnostic accuracy.European radiology · 2020Trial
- Double-low protocol for hepatic dynamic CT scan: Effect of low tube voltage and low-dose iodine contrast agent on image quality.Medicine · 2016Trial
- Dual Energy CT Angiography of Peripheral Arterial Disease: Feasibility of Using Lower Contrast Medium Volume.PloS one · 2015Trial
- Reduced radiation dose and improved image quality at cardiovascular CT angiography by automated attenuation-based tube voltage selection: intra-individual comparison.European radiology · 2014Trial
- Feasibility of 80-kVp CTA with reduced iodine contrast in chronic limb-threatening ischemia.Medicine · 2026Article
- Image quality, contrast enhancement and radiation dose of electrocardiograph- versus non-electrocardiograph-triggered computed tomography angiography of the aorta.Singapore medical journal · 2024Article
- Basic Concepts of Contrast Injection Protocols for Coronary Computed Tomography Angiography.Current cardiology reviews · 2019Review
- CT Angiography in the Lower Extremity Peripheral Artery Disease Feasibility of an Ultra-Low Volume Contrast Media Protocol.Cardiovascular and interventional radiology · 2018Article
- Using 80 kVp on a 320-row scanner for hepatic multiphasic CT reduces the contrast dose by 50 % in patients at risk for contrast-induced nephropathy.European radiology · 2017Article
- Advances in axial imaging of peripheral vascular disease.Current cardiology reports · 2015Review
- Surveillance Imaging Following Endovascular Aneurysm Repair.Seminars in interventional radiology · 2015Review
- Low contrast dose protocol involving a 100 kVp tube voltage for hypervascular hepatocellular carcinoma in patients with renal dysfunction.Japanese journal of radiology · 2015Article
- Contrast agent and radiation dose reduction in abdominal CT by a combination of low tube voltage and advanced image reconstruction algorithms.European radiology · 2015Article
- Article
- Article
- Article
- Effect of hybrid iterative reconstruction technique on quantitative and qualitative image analysis at 256-slice prospective gating cardiac CT.European radiology · 2012Article
- Diagnostic cross-sectional imaging of arterial diseases: really noninvasive?European radiology · 2011Article
- Combination of a low-tube-voltage technique with hybrid iterative reconstruction (iDose) algorithm at coronary computed tomographic angiography.Journal of computer assisted tomographyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe investigated the effect of low-tube-voltage CT angiography with a reduced volume of contrast agent on qualitative and quantitative parameters and the radiation dose in patients with peripheral arterial disease.
methodsEighty consecutive patients were divided into two groups; the protocol was 120 kVp and 1.8 ml/kg contrast agent (300 mgI/ml) in one group and 80 kVp and 1.2 ml/kg in the other. For quantitative analysis we calculated the mean arterial attenuation, the mean difference between maximum and minimum attenuation values, contrast-to-noise ratio (CNR), and figure of merit (FOM). For qualitative evaluation, we used visual scores.
resultsThere were no significant intergroup differences in mean arterial attenuation (120 vs. 80 kVp: 331.6 ± 61.6 vs. 354.9 ± 61.9 HU) and in the mean difference between maximum and minimum attenuation (120 vs. 80 kVp: 52.2 ± 25.5 vs. 61.5 ± 27.5 HU). While the mean CNR was significantly higher at 120 than 80 kVp (38.4 ± 18.8 vs. 31.1 ± 15.3), the mean FOM was not significantly different (120 vs. 80 kVp: 1.3 ± 1.5 vs. 1.2 ± 1.2), and there was no significant intergroup difference in visual scores. The mean dose-length product was significantly lower at 80 than 120 kVp (1,024.3 ± 151.3 vs. 1,464.7 ± 208.7 mGy·cm).
conclusionThe 80-kVp protocol allows for reduction of the radiation dose by approximately 30% and the volume of contrast agent by more than 30% without deterioration of vascular enhancement and image quality.
Indexed as
Identifiers
20571804What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.