ArticleSocial science & medicine (1982)2011
Postgenomics, uncertain futures, and the familiarization of susceptibility genes.
Article in Social science & medicine (1982), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Psychological, behavioral and social effects of disclosing Alzheimer's disease biomarkers to research participants: a systematic review.Alzheimer's research & therapy · 2016Pooled it
- Taking after a parent: Phenotypic resemblance and the professional familialisation of genomics.Sociology of health & illness · 2024Article
- "Why did I get that part of you?" Understanding addiction genetics through family history.Public understanding of science (Bristol, England) · 2019Article
- Perspectives on Communicating Biomarker-Based Assessments of Alzheimer's Disease to Cognitively Healthy Individuals.Journal of Alzheimer's disease : JAD · 2018Article
- "I don't have to know why it snows, I just have to shovel it!": Addiction Recovery, Genetic Frameworks, and Biological Citizenship.BioSocieties · 2017Article
- Converging approaches to understanding early onset familial Alzheimer disease: A First Nation study.SAGE open medicine · 2015Article
- Before it is too late: professional responsibilities in late-onset Alzheimer's research and pre-symptomatic prediction.Frontiers in human neuroscience · 2014Article
- A review of quality of life after predictive testing for and earlier identification of neurodegenerative diseases.Progress in neurobiology · 2013Review
- Article
- Holding blame at bay? 'Gene talk' in family members' accounts of schizophrenia aetiology.BioSocieties · 2012Article
- "My funky genetics": BRCA1/2 mutation carriers' understanding of genetic inheritance and reproductive merger in the context of new reprogenetic technologies.Families, systems & health : the journal of collaborative family healthcare · 2012Article
- The evolving classification of dementia: placing the DSM-V in a meaningful historical and cultural context and pondering the future of "Alzheimer's".Culture, medicine and psychiatry · 2011Article
- Genetic counselling for personalised medicine.Human genetics · 2011Article
- The clinical utility of gene testing for Alzheimer's disease.Neurology international · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
This paper draws on empirical findings from interview studies in the USA and Canada to interrogate the idea that expanding practices of genetic testing are likely to transform kin and family relations in fundamental ways. We argue that in connection with common adult onset disorders in which susceptibility genes with low predictive power are implicated it is unlikely that family relationships will be radically altered as a result of learning about either individual or family genotypes. Rather, pre-existing family dynamics and ideas about family susceptibilities for disease may be reinforced. The case of the ApoE gene and its relationship to Alzheimer's disease is used as an illustrative example. We found that "postgenomic" thinking, in which complexity of disease causation is emphasized, is readily apparent in informant narratives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.