ReviewBioTechniques2010
Controlling transcription with noncoding RNAs in mammalian cells.
Review in BioTechniques, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Riding the Wave of Progress: Examining the Current Landscape and Future Potential of MicroRNAs in Cancer Gene Therapy.Current gene therapy · 2026Review
- Creation of the HIV-1 antisense geneMicrobiology spectrum · 2024Article
- Modulating epigenetic modifications for cancer therapy (Review).Oncology reports · 2023Review
- Biological roles and therapeutic potential of circular RNAs in osteoarthritis.Molecular therapy. Nucleic acids · 2021Review
- RNA activation of haploinsufficient Foxg1 gene in murine neocortex.Scientific reports · 2016Article
- Transcriptional gene silencing in humans.Nucleic acids research · 2016Article
- RNA-directed epigenetic silencing of Periostin inhibits cell motility.Royal Society open science · 2015Article
- MYCNOS functions as an antisense RNA regulating MYCN.RNA biology · 2015Article
- The theory of RNA-mediated gene evolution.Epigenetics · 2015Review
- The present and future of prostate cancer urine biomarkers.International journal of molecular sciences · 2013Review
- LncRNAs have a say in protein translation.Cell research · 2013Article
- Long non-coding RNA targeting and transcriptional de-repression.Nucleic acid therapeutics · 2013Review
- Epigenetics and bacterial infections.Cold Spring Harbor perspectives in medicine · 2012Review
- Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells.Nature structural & molecular biology · 2012Article
- Article
- Article
- Characterization of an HIV-targeted transcriptional gene-silencing RNA in primary cells.Human gene therapy · 2012Article
- Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors.Clinical epigenetics · 2012Article
- The role of peroxisome proliferator-activated receptors in the esophageal, gastric, and colorectal cancer.PPAR research · 2012Article
- Life or death? A physiogenomic approach to understand individual variation in responses to hemorrhagic shock.Current genomics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Emerging research suggests that long noncoding RNAs (ncRNAs) may play a role in the basic fabric of gene regulation in human cells. Mechanistic studies carried out on a small subset of antisense ncRNAs have begun to link RNA-mediated modifications of DNA and chromatin structure with gene expression, implicating ncRNAs in the regulation of transcription. Meanwhile, genome-wide studies have revealed that transcription of ncRNAs is far more ubiquitous than previously thought and suggest a more pervasive role for ncRNAs. This review will describe the current state of research regarding gene regulation by ncRNAs and highlight major techniques used in the field. Furthermore, the potential for therapeutic applications based on ncRNA regulation will also be discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.