Evidence map›Paper›PMID 20566621›Full record

ArticleThe Journal of clinical endocrinology and metabolism2010

Correlation of serum androgens with anthropometric and metabolic indices in healthy, nonobese postmenopausal women.

Peter R Casson, Michael J Toth, Julia V Johnson, Frank Z Stanczyk, Colleen L Casey, Marjorie E Dixon

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Menopause and risk of diabetes in the Diabetes Prevention Program.Menopause (New York, N.Y.) · 2011 · on this map
    Trial
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Peter R CassonUniversity of Vermont, Fletcher Allen Health Care, Smith 401, 111 Colchester Avenue, Burlington, Vermont 05401, USA. peter.casson@vtmednet.org
Michael J Toth
Julia V Johnson
Frank Z Stanczyk
Colleen L Casey
Marjorie E Dixon
University of Vermont · USUniversity of Southern California · US

Funding

WEIGHT MAINTENANCE AND PSYCHOLOGICAL BENEFITS OF EXERCISEM01RR000109 · NCRR · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI STAPLETON, RENEE D · 1985 to 2010
$24.3M
NCRR NIH HHS M01 RR000109NCRR NIH HHS M01 RR00109
6 · The paper itself

Abstract

objectiveThe role of testosterone in the regulation of metabolic and physiological function in men is well defined, but its role in women remains enigmatic. Thus, the present study sought to assess the contribution of endogenous circulating androgens to the regulation of metabolic function, body morphometry, and physical function in normal naturally postmenopausal women.

methodsUsing a cross-sectional design, we measured serum androgens in a cohort of 29 naturally postmenopausal women and correlated the results with metabolic, morphometric, and functional outcome parameters. These included insulin sensitivity, whole-body fat and lean body mass, visceral/abdominal fat areasm and aerobic capacity.

resultsHigher serum testosterone levels were related to greater maximal aerobic capacity and reduced adiposity. Additionally, higher serum dihydrotestosterone, dehydroepiandrosterone sulfate, androstenedione, and androstenetriol glucuronidate levels were correlated to greater insulin sensitivity.

conclusionIn naturally postmenopausal women, endogenous androgens may play a role in the maintenance of beneficial patterns of metabolic, morphometric, and functional parameters.

Indexed as

Body Weights and MeasuresMetabolomeAgedAndrogensCohort StudiesCross-Sectional StudiesFemaleHealthHealth Status IndicatorsHumansIdeal Body WeightMaleMiddle AgedPostmenopauseStatistics as TopicTestosteroneAndrogensTestosterone

Identifiers

PMID20566621
PMCPMC2936067
OpenAlexW2050842063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.