ReviewPediatrics2010
Procession to pediatric bacteremia and sepsis: covert operations and failures in diplomacy.
Review in Pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 56 citations in OpenAlex.
- Diagnostic value of procalcitonin and hemocyte parameters in neonates with bloodstream infection: Role of activated hemocyte-related genes.Pediatric discovery · 2024Article
- Emergence ofAfrican journal of medicine and medical sciences · 2023Article
- Article
- HMGB1 mediates acute liver injury in sepsis through pyroptosis of liver macrophages.International journal of burns and trauma · 2020Article
- Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide.Scientific reports · 2019Article
- Precision Medicine for Neonatal Sepsis.Frontiers in molecular biosciences · 2018Review
- Diagnosis of Bloodstream Infections in Children.Journal of clinical microbiology · 2016Review
- Inflammatory Response in Preterm and Very Preterm Newborns with Sepsis.Mediators of inflammation · 2016Article
- Bacteremia in Early Infancy: Etiology and Management.Current infectious disease reports · 2016Article
- Translation of clinical prediction rules for febrile children to primary care practice: an observational cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015Observational
- Prevalence, clinical features, and outcome of pseudomonas bacteremia in under-five diarrheal children in bangladesh.ISRN microbiology · 2014Article
- Use of alarm features in referral of febrile children to the emergency department: an observational study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014Observational
- Ampicillin and gentamicin are a useful first-line combination for the management of sepsis in under-five children at an urban hospital in Bangladesh.Journal of health, population, and nutrition · 2012Article
- Community faecal carriage of extended-spectrum beta-lactamase-producing Enterobacteriaceae in French children.BMC infectious diseases · 2012Article
- Gut microbial translocation in critically ill children and effects of supplementation with pre- and pro biotics.International journal of microbiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Despite advances in diagnosis and treatment, bacterial sepsis remains a major cause of pediatric morbidity and mortality, particularly among neonates, the critically ill, and the growing immunocompromised patient population. Sepsis is the end point of a complex and dynamic series of events in which both host and microbial factors drive high morbidity and potentially lethal physiologic alterations. In this article we provide a succinct overview of the events that lead to pediatric bloodstream infections (BSIs) and sepsis, with a focus on the molecular mechanisms used by bacteria to subvert host barriers and local immunity to gain access to and persist within the systemic circulation. In the events preceding and during BSI and sepsis, Gram-positive and Gram-negative pathogens use a battery of factors for translocation, inhibition of immunity, molecular mimicry, intracellular survival, and nutrient scavenging. Gaps in understanding the molecular pathogenesis of bacterial BSIs and sepsis are highlighted as opportunities to identify and develop new therapeutics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.