Evidence map›Paper›PMID 20566281›Full record

ReviewCurrent opinion in genetics & development2010

Cellular dynamics in the early mouse embryo: from axis formation to gastrulation.

Sonja Nowotschin, Anna-Katerina Hadjantonakis

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
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  7. Review
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  9. Article
  10. Insight intoInternational journal of molecular sciences · 2019
    Article
  11. Article
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  13. Article
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  15. Article
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  18. Self-Organization of Spatial Patterning in Human Embryonic Stem Cells.Current topics in developmental biology · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sonja NowotschinDevelopmental Biology Program, Sloan-Kettering Institute, New York, NY 10065, USA.
Anna-Katerina Hadjantonakis

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Morphogenesis of the paraxial mesoderm in miceR01HD052115 · NICHD · SLOAN-KETTERING INST CAN RESEARCH · PI HADJANTONAKIS, ANNA-KATERINA · 2006 to 2015
$4.1M
Morphogenesis of mammalian gut endodermR01DK084391 · NIDDK · SLOAN-KETTERING INST CAN RESEARCH · PI HADJANTONAKIS, ANNA-KATERINA · 2009 to 2018
$4.1M
NCI NIH HHS P30 CA008748NICHD NIH HHS R01 HD052115NIDDK NIH HHS R01 DK084391
6 · The paper itself

Abstract

Coordinated cell movements and reciprocal tissue interactions direct the formation of the definitive germ layers and the elaboration of the major axes of the mouse embryo. Genetic and embryological studies have defined the major molecular pathways that mediate these morphogenetic processes and provided 'snapshots' of the morphogenetic program. However, it is increasingly clear that this foundation needs to be validated, and can be significantly refined and extended using live imaging approaches. In situ visualization of these processes in living specimens is a major goal, as it provides unprecedented detail of the individual cellular behaviors, which translate into the large-scale tissue rearrangements that shape the embryo.

Indexed as

Body PatterningGastrulationAnimalsCell CommunicationCell LineageCell MovementCell PolarityEmbryo, MammalianEmbryonic DevelopmentMiceSignal Transduction

Identifiers

PMID20566281
PMCPMC2908213

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.