ArticleBMC plant biology2010
Changes in the proteomic and metabolic profiles of Beta vulgaris root tips in response to iron deficiency and resupply.
Article in BMC plant biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 121 citations in OpenAlex.
- Molecular Mechanism by Which the BrFIT2-BrbHLH-BrIRT1 Module Synergistically Regulates Iron Absorption in Brassica rapa ssp. Pekinensis.Plant biotechnology journal · 2025Article
- Flavin-dependent enzymatic and photochemical interconversions between phenylarsonic and phenylarsonous acids.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- The activation of iron deficiency responses of grapevine rootstocks is dependent to the availability of the nitrogen forms.BMC plant biology · 2024Article
- Coated Hematite Nanoparticles Alleviate Iron Deficiency in Cucumber in Acidic Nutrient Solution and as Foliar Spray.Plants (Basel, Switzerland) · 2023Article
- Metabolomics analysis reveals changes related to pseudocyst formation induced by iron depletion in Trichomonas vaginalis.Parasites & vectors · 2023Article
- Biotic stress-induced changes in root exudation confer plant stress tolerance by altering rhizospheric microbial community.Frontiers in plant science · 2023Review
- A systematicFrontiers in plant science · 2023Article
- Biotechnological Interventions in Tomato (Biotech (Basel (Switzerland)) · 2022Review
- Effects of Fe and Mn Deficiencies on the Root Protein Profiles of Tomato (International journal of molecular sciences · 2022Article
- Comparative proteome analyses of rhizomania resistant transgenic sugar beets based on RNA silencing mechanism.GM crops & food · 2021Article
- Changes in organic compounds secreted by roots in two Poaceae species (Hordeum vulgare and Polypogon monspenliensis) subjected to iron deficiency.Journal of plant research · 2021Article
- Single and Combined Fe and S Deficiency Differentially Modulate Root Exudate Composition in Tomato: A Double Strategy for Fe Acquisition?International journal of molecular sciences · 2020Article
- Photosynthetic Carbon Partitioning and Metabolic Regulation in Response to Very-Low and High COFrontiers in plant science · 2020Article
- Common and specific responses to iron and phosphorus deficiencies in roots of apple tree (Malus × domestica).Plant molecular biology · 2019Article
- Article
- Adaption of Roots to Nitrogen Deficiency Revealed by 3D Quantification and Proteomic Analysis.Plant physiology · 2019Article
- Genotypic Variation in the Root and Shoot Metabolite Profiles of Wheat (Frontiers in plant science · 2019Article
- Transcriptome analysis in Malus halliana roots in response to iron deficiency reveals insight into sugar regulation.Molecular genetics and genomics : MGG · 2018Article
- Gene Expression Profiling of Iron Deficiency Chlorosis Sensitive and Tolerant Soybean Indicates Key Roles for Phenylpropanoids under Alkalinity Stress.Frontiers in plant science · 2018Article
- NMR-Based Metabolic Profiling of Field-Grown Leaves from Sugar Beet Plants Harbouring Different Levels of Resistance to Cercospora Leaf Spot Disease.Metabolites · 2017Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlants grown under iron deficiency show different morphological, biochemical and physiological changes. These changes include, among others, the elicitation of different strategies to improve the acquisition of Fe from the rhizosphere, the adjustment of Fe homeostasis processes and a reorganization of carbohydrate metabolism. The application of modern techniques that allow the simultaneous and untargeted analysis of multiple proteins and metabolites can provide insight into multiple processes taking place in plants under Fe deficiency. The objective of this study was to characterize the changes induced in the root tip proteome and metabolome of sugar beet plants in response to Fe deficiency and resupply.
resultsRoot tip extract proteome maps were obtained by 2-D isoelectric focusing polyacrylamide gel electrophoresis, and approximately 140 spots were detected. Iron deficiency resulted in changes in the relative amounts of 61 polypeptides, and 22 of them were identified by mass spectrometry (MS). Metabolites in root tip extracts were analyzed by gas chromatography-MS, and more than 300 metabolites were resolved. Out of 77 identified metabolites, 26 changed significantly with Fe deficiency. Iron deficiency induced increases in the relative amounts of proteins and metabolites associated to glycolysis, tri-carboxylic acid cycle and anaerobic respiration, confirming previous studies. Furthermore, a protein not present in Fe-sufficient roots, dimethyl-8-ribityllumazine (DMRL) synthase, was present in high amounts in root tips from Fe-deficient sugar beet plants and gene transcript levels were higher in Fe-deficient root tips. Also, a marked increase in the relative amounts of the raffinose family of oligosaccharides (RFOs) was observed in Fe-deficient plants, and a further increase in these compounds occurred upon short term Fe resupply.
conclusionsThe increases in DMRL synthase and in RFO sugars were the major changes induced by Fe deficiency and resupply in root tips of sugar beet plants. Flavin synthesis could be involved in Fe uptake, whereas RFO sugars could be involved in the alleviation of oxidative stress, C trafficking or cell signalling. Our data also confirm the increase in proteins and metabolites related to carbohydrate metabolism and TCA cycle pathways.
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