Trial reportJournal of experimental & clinical cancer research : CR2010
Alterations of dendritic cell subsets in the peripheral circulation of patients with cervical carcinoma.
Trial report in Journal of experimental & clinical cancer research : CR, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Article
- Immunogenomic Identification for Predicting the Prognosis of Cervical Cancer Patients.International journal of molecular sciences · 2021Article
- Clinical significance of peripheral blood and tumor tissue lymphocyte subsets in cervical cancer patients.BMC cancer · 2020Article
- Engineering an Artificial T-Cell Stimulating Matrix for Immunotherapy.Advanced materials (Deerfield Beach, Fla.) · 2019Article
- Engineering Platforms for T Cell Modulation.International review of cell and molecular biology · 2018Review
- Biologically Inspired Design of Nanoparticle Artificial Antigen-Presenting Cells for Immunomodulation.Nano letters · 2017Article
- hrHPV E5 oncoprotein: immune evasion and related immunotherapies.Journal of experimental & clinical cancer research : CR · 2017Review
- Myeloid dendritic cells are decreased in peripheral blood of Alzheimer's disease patients in association with disease progression and severity of depressive symptoms.Journal of neuroinflammation · 2016Article
- Review
- The effect of environmental chemicals on the tumor microenvironment.Carcinogenesis · 2015Review
- Linking form to function: Biophysical aspects of artificial antigen presenting cell design.Biochimica et biophysica acta · 2015Review
- Lymphocyte subpopulation and dendritic cell phenotyping during antineoplastic therapy in human solid tumors.Clinical and experimental medicine · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with cervical carcinoma (CC) are frequently immunocompromised. Dendritic cells (DCs) are potent antigen-presenting cells. Using multicolor flow cytometry, the percentages of CD11c+ (DC1) and CD123+ (DC2) subsets, were determined in the peripheral blood of 37 patients with cervical carcinoma (CC), 54 patients with CIN, and 62 healthy individuals. A substantial reduction of circulating dendritic cells and accordingly immunodepression may be associated with increased IL-6 and TGF-beta in serum. These findings could give expression to the immunosuppression of circulating dendritic cells in patients with CC and CIN, thus, may indicate novel aspects of cervical carcinoma immune evasion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.