Evidence map›Paper›PMID 20565823›Full record

ArticleTheoretical biology & medical modelling2010

Skeletal muscle contraction. The thorough definition of the contractile event requires both load acceleration and load mass to be known.

Enrico Grazi, Sara Pozzati

Abstract read
In one paragraph

Article in Theoretical biology & medical modelling, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Enrico GraziDipartimento di Biochimica e Biologia Molecolare, Università di Ferrara, Via Borsari 46, 44100, Ferrara, Italy. enrico.grazi@unife.it
Sara Pozzati

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe scope of this work is to show that the correct and complete definition of the system of muscle contraction requires the knowledge of both the mass and the acceleration of the load.

resultsThe aim is achieved by making use of a model of muscle contraction that operates into two phases. The first phase considers the effects of the power stroke in the absence of any hindrance. In the second phase viscous hindrance is introduced to match the experimental speed and yield of the contraction. It is shown that, at constant force of the load, changing load acceleration changes the time course of the pre-steady state of myofibril contraction. The decrease of the acceleration of the load from 9.8 m.s(-2) to 1 m.s(-2) increases the time length of the pre-steady state of the contraction from a few microseconds to many hundreds of microseconds and decreases the stiffness of the active fibre.

conclusionsWe urge that in the study of muscle contraction both the mass and the acceleration of the load are specified.

Indexed as

Adenosine TriphosphatasesAnimalsKineticsMuscle ContractionMuscle, SkeletalOrgan SizeSarcomeresWeight-BearingAdenosine Triphosphatases

Identifiers

PMID20565823
PMCPMC2900230

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.