ReviewRespiratory research2010
Outcome measures in chronic obstructive pulmonary disease (COPD): strengths and limitations.
Review in Respiratory research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Respiratory health effects of e-cigarette substitution for tobacco cigarettes: a systematic review.Harm reduction journal · 2023Pooled it
- Comorbidity in adults with traumatic brain injury and all-cause mortality: a systematic review.BMJ open · 2019Pooled it
- Pooled it
- Treatment of acute exacerbations of chronic obstructive pulmonary disease with acupuncture during hospitalization: a three-arm double-blinded randomized sham-controlled trial.Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2022Trial
- A dose-ranging study of the inhaled dual phosphodiesterase 3 and 4 inhibitor ensifentrine in COPD.Respiratory research · 2020Trial
- Trial
- A monitoring and feedback tool embedded in a counselling protocol to increase physical activity of patients with COPD or type 2 diabetes in primary care: study protocol of a three-arm cluster randomised controlled trial.BMC family practice · 2014Trial
- Changes in physical activity in healthy people and COPD patients.Wiener klinische Wochenschrift · 2014Trial
- Putting health status guided COPD management to the test: protocol of the MARCH study.BMC pulmonary medicine · 2013Trial
- Eight-step method to build the clinical content of an evidence-based care pathway: the case for COPD exacerbation.Trials · 2012Trial
- Participant-selected music listening during pulmonary rehabilitation in people with chronic obstructive pulmonary disease: A randomised controlled trial.Chronic respiratory diseaseTrial
- Clinical impact of disease stability on exacerbation and mortality in COPD: a retrospective cohort study.Annals of medicine · 2026Article
- Article
- Depression and Anxiety as Comorbidities in Chronic Obstructive Pulmonary Disease: A Comprehensive Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- Validation of the modified BODE index using the activity domain of St George's Respiratory Questionnaire.ERJ open research · 2025Article
- Unveiling the burden of COPD: perspectives on a patient-reported outcome measure to support communication in outpatient consultations-an interview study among patients.Frontiers in rehabilitation sciences · 2024Article
- Personalizing Selection of Inhaled Delivery Systems in Chronic Obstructive Pulmonary Disease.Annals of the American Thoracic Society · 2023Review
- Systems Engineering Approach to Modeling and Analysis of Chronic Obstructive Pulmonary Disease.ACS omega · 2023Article
- Artificial intelligence based software facilitates spirometry quality control in asthma and COPD clinical trials.ERJ open research · 2023Article
- The Inventory of Physical Activity Barriers for Adults 50 Years and Older: Refinement and Validation.The Gerontologist · 2022Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current methods for assessing clinical outcomes in COPD mainly rely on physiological tests combined with the use of questionnaires. The present review considers commonly used outcome measures such as lung function, health status, exercise capacity and physical activity, dyspnoea, exacerbations, the multi-dimensional BODE score, and mortality. Based on current published data, we provide a concise overview of the principles, strengths and weaknesses, and discuss open questions related to each methodology. Reviewed is the current set of markers for measuring clinically relevant outcomes with particular emphasis on their limitations and opportunities that should be recognized when assessing and interpreting their use in clinical trials of COPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.