ArticleJournal of molecular evolution2010
Sequence polymorphism and geographical variation at a positively selected MHC-DRB gene in the finless porpoise (Neophocaena phocaenoides): implication for recent differentiation of the Yangtze finless porpoise?
Article in Journal of molecular evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 25 citations in OpenAlex.
- TheAnimals : an open access journal from MDPI · 2019Article
- Distinct evolution of toll-like receptor signaling pathway genes in cetaceans.Genes & genomics · 2019Article
- Divergent Evolution of TRC Genes in Mammalian Niche Adaptation.Frontiers in immunology · 2019Article
- Article
- Organization and characteristics of the major histocompatibility complex class II region in the Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis).Scientific reports · 2016Article
- Genetic Variation at Exon 2 of the MHC Class II DQB Locus in Blue Whale (Balaenoptera musculus) from the Gulf of California.PloS one · 2016Article
- Evolution by selection, recombination, and gene duplication in MHC class I genes of two Rhacophoridae species.BMC evolutionary biology · 2013Article
- Balancing selection and genetic drift at major histocompatibility complex class II genes in isolated populations of golden snub-nosed monkey (Rhinopithecus roxellana).BMC evolutionary biology · 2012Article
- Extremely high major histocompatibility complex class IIb gene intron 2 variation and population structure in Chinese alligator.Journal of genetics · 2012Article
- Considerable MHC diversity suggests that the functional extinction of baiji is not related to population genetic collapse.PloS one · 2012Article
- Relationship between Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism and Susceptibility of Minimal Change Nephrotic Syndrome: A Meta-Analysis.International journal of nephrology · 2011Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
Sequence polymorphism at the MHC class II DRB locus was investigated in three finless porpoise (Neophocaena phocaenoides) populations in Chinese waters. Intragenic recombination and strong positive selection were the main forces in generating sequence diversity in the DRB gene. MHC sequence diversity changed significantly along the study period. Significant decrease in heterozygosity and lost alleles have been detected in the Yangtze River population and South China Sea population since 1990. Furthermore, there is a trend of increasing population differentiation over time. Especially, the genetic differentiation between the Yangtze River population and the Yellow Sea population was very low prior to 1990 (F (ST) = 0.036, P = 0.009), but became very significant after 1990 (F (ST) = 0.134, P < 0.001), suggesting a recent augmentation of genetic differentiation between both populations probably in a relatively short-term period. Porpoises from the Yangtze River displayed divergent frequencies of shared and private alleles from those displayed by two marine populations, which suggest that the former riverine population has been under a different selection regime (characteristic of a fresh water environment) than that of its marine counterparts.
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