ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2010
Clinical characteristics of viral intestinal infection in preterm and term neonates.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 60 citations in OpenAlex.
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- Bile acid-sensitive human norovirus strains are susceptible to sphingosine-1-phosphate receptor 2 inhibition.Journal of virology · 2024Article
- Phenol Derivatives Obtained from Grape Seed Extract Show Virucidal Activity against Murine Norovirus.Molecules (Basel, Switzerland) · 2022Article
- Epidemiology, Clinical Features, and Unusual Complications of Norovirus Infection in Taiwan: What We Know after Rotavirus Vaccines.Pathogens (Basel, Switzerland) · 2022Review
- Virucidal and Immunostimulating Activities of Monogalactosyl Diacylglyceride fromMarine drugs · 2022Article
- Glycan Recognition in Human Norovirus Infections.Viruses · 2021Review
- Temporal and seasonal variations in incidence of stage II and III NEC-a 28-year epidemiologic study from tertiary NICUs in Connecticut, USA.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Necrotizing Enterocolitis in Neonates With Hyperinsulinemic Hypoglycemia Treated With Diazoxide.Pediatrics · 2021Article
- Norovirus encounters in the gut: multifaceted interactions and disease outcomes.Mucosal immunology · 2019Review
- In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase.Scientific reports · 2018Article
- Review
- The viral dsRNA analogue poly (I:C) induces necrotizing enterocolitis in neonatal mice.Pediatric research · 2016Article
- Norovirus immunology: Of mice and mechanisms.European journal of immunology · 2015Review
- Depth of bacterial invasion in resected intestinal tissue predicts mortality in surgical necrotizing enterocolitis.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
- Infectious causes of necrotizing enterocolitis.Clinics in perinatology · 2015Review
- Intestinal necrosis due to norovirus enteritis.Clinical journal of gastroenterology · 2015Article
- Norovirus.Clinical microbiology reviews · 2015Review
- Acute gastroenteritis and enteric viruses in hospitalised children in southern Brazil: aetiology, seasonality and clinical outcomes.Memorias do Instituto Oswaldo Cruz · 2014Article
- Targeted rotavirus vaccination of high-risk infants; a low cost and highly cost-effective alternative to universal vaccination.BMC medicine · 2013Article
- Isolated colon ischemia with norovirus infection in preterm babies: a case series.Journal of medical case reports · 2013Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical presentation of the viral enteric pathogens in newborn infants has not been adequately examined. The aim of this study was to evaluate the clinical characteristics of viral intestinal infections in newborn infants. Clinical data of all term and preterm infants admitted to our tertiary neonatal intensive care unit from 1998 to 2007 with clinical signs of gastroenteritis (GE) or necrotizing enterocolitis (NEC) were retrospectively reviewed and compared between infants with different viral enteric pathogens in stool specimens. In 34 infants with signs of GE or NEC, enteropathogenic viruses were found in stool specimens. Rotavirus was detected in 12 cases, of which two infants had NEC. Compared with infants with rotavirus or norovirus, infants with astrovirus more frequently suffered from NEC (p<0.05). In addition, an acute systemic inflammatory response was significantly more common in patients with astrovirus infection (astrovirus vs. rotavirus and astrovirus vs. norovirus, p < 0.01 and p < 0.05, respectively). Of eight children infected with norovirus, one infant had a systemic acute inflammatory response and NEC. This study demonstrates that in newborn infants, intestinal rotavirus, norovirus, and astrovirus infections may be associated with severe illness such as hemorrhagic enteritis resulting in bloody diarrhea or even NEC.
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