ArticleTicks and tick-borne diseases2010
Quantum of infection of Francisella tularensis tularensis in host-seeking Dermacentor variabilis.
Article in Ticks and tick-borne diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Genetic diversity and phylogeographic relationships of Dermacentor variabilis (Acari: Ixodidae) within an established population in southern Manitoba (Canada), and the prevalence of Rickettsia montanensis and Francisella-like endosymbionts.Journal of medical entomology · 2025Article
- Tick extracellular vesicles enable arthropod feeding and promote distinct outcomes of bacterial infection.Nature communications · 2021Article
- APathogens (Basel, Switzerland) · 2020Article
- Mechanisms Affecting the Acquisition, Persistence and Transmission ofMicroorganisms · 2020Review
- Ticks and Tularemia: Do We Know What We Don't Know?Frontiers in cellular and infection microbiology · 2019Review
- Article
- Serological investigation of wild boars (Sus scrofa) and red foxes (Vulpes vulpes) as indicator animals for circulation of Francisella tularensis in Germany.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2014Article
- Tularaemia seroprevalence of captured and wild animals in Germany: the fox (Vulpes vulpes) as a biological indicator.Epidemiology and infection · 2013Article
- Association of different genetic types of Francisella-like organisms with the rocky mountain wood tick (Dermacentor andersoni) and the American dog tick (Dermacentor variabilis) in localities near their northern distributional limits.Applied and environmental microbiology · 2012Article
- Biology of Francisella tularensis subspecies holarctica live vaccine strain in the tick vector Dermacentor variabilis.PloS one · 2012Article
- Differential mortality of dog tick vectors due to infection by diverse Francisella tularensis tularensis genotypes.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2011Article
- Ecology of Tularemia in Central US Endemic Region.Current tropical medicine reportsReview
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The American dog tick, Dermacentor variabilis, is fundamental to the perpetuation of Francisella tularensis tularensis on Martha's Vineyard, Massachusetts, U.S.A. Although infected ticks are relatively common on the island, human cases deriving from tick bite are rare. It may be that the quantum of bacteria within these naturally infected ticks is frequently too small to cause disease. Accordingly, we quantified the amount of F.t. tularensis bacteria in host-seeking ticks from the island. Contrary to our expectations, the majority of the ticks harbor large numbers of bacteria (median 3.3x10(8) genome equivalents/tick). Such a large quantum of infection might suggest that aerosolization of the ticks themselves might comprise the proximal determinant of risk for the inhalational tularemia that is common on Martha's Vineyard. However, the paradox of fewer ulceroglandular tularemia cases than would be expected given the abundance of potentially highly infectious ticks remains to be solved.
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Registered trials
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