Evidence map›Paper›PMID 20561815›Full record

ReviewCurrent opinion in microbiology2010

Chitin synthesis and fungal pathogenesis.

Megan D Lenardon, Carol A Munro, Neil A R Gow

Open access · hybridAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 220 papers.

0numbers the graph read from it
0cells of the map it votes in
220citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

220 citing papers in PubMed, 477 citations in OpenAlex.

  1. Plant signaling & behavior · 2026
    Article
  2. Review
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  15. Review
  16. Antifungal Potential ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  17. Article
  18. Frontiers in microbiology · 2026
    Review
  19. Article
  20. Current Insights intoJournal of fungi (Basel, Switzerland) · 2025
    Article

160 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Megan D LenardonAberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
Carol A Munro
Neil A R Gow
University of Aberdeen · GB

Funding

Biotechnology and Biological Sciences Research Council BB/C510191/1Medical Research Council G0400284Wellcome Trust
6 · The paper itself

Abstract

Chitin is an essential part of the carbohydrate skeleton of the fungal cell wall and is a molecule that is not represented in humans and other vertebrates. Complex regulatory mechanisms enable chitin to be positioned at specific sites throughout the cell cycle to maintain the overall strength of the wall and enable rapid, life-saving modifications to be made under cell wall stress conditions. Chitin has also recently emerged as a significant player in the activation and attenuation of immune responses to fungi and other chitin-containing parasites. This review summarises latest advances in the analysis of chitin synthesis regulation in the context of fungal pathogenesis.

Indexed as

AnimalsAntifungal Agentsbeta-GlucansCell WallChitinDrug DesignFungiGene Expression Regulation, FungalHost-Pathogen InteractionsHumansMycosesAntifungal Agentsbeta-GlucansChitin

Identifiers

PMID20561815
PMCPMC2923753
OpenAlexW2130963153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.