ArticleInternational journal of hematology2010
Significance of plasma D-dimer in relation to the severity of atherosclerosis among patients evaluated by non-invasive indices of cardio-ankle vascular index and carotid intima-media thickness.
Article in International journal of hematology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Associations of High-Sensitivity Cardiac Troponin T, D-Dimer, and N-Terminal Pro-B-Type Natriuretic Peptide with Subclinical Cardiovascular Dysfunction in the General Population: A Retrospective Cross-Sectional Study.Vascular health and risk management · 2026Article
- Long-term Effects of COVID-19 on Vascular Parameters-A Prospective Longitudinal Ultrasound Clinical Study.Journal for vascular ultrasound : JVU · 2024Article
- Urinary Immunoglobulin G Is a Novel Biomarker for Atherosclerotic Burden in Mild Acute Ischemic Stroke Patients.Journal of atherosclerosis and thrombosis · 2024Article
- Sitagliptin on carotid intima-media thickness in type 2 diabetes and hyperuricemia patients: a subgroup analysis of the PROLOGUE study.Therapeutic advances in chronic disease · 2021Article
- Observational
- Association between Fibrinogen and Carotid Atherosclerosis According to Smoking Status in a Korean Male Population.Yonsei medical journal · 2015Article
- Cardio-ankle vascular index (CAVI) as an indicator of arterial stiffness.Integrated blood pressure control · 2013Article
- Association of cardio-ankle vascular index with physical fitness and cognitive symptoms in aging Finnish firefighters.International archives of occupational and environmental health · 2012Article
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Authors and funding
1 author.
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Abstract
The aim of this study is to elucidate the usefulness of plasma D-dimer for the prediction of thrombotic events in highly atherosclerotic patients. The severity of atherosclerosis was measured by non-invasive methods including cardio-ankle vascular index (CAVI) and carotid intima-media thickness (IMT) in 100 patients with atherosclerosis aged 72.1 years on average. CAVI was significantly correlated with the levels of D-dimer, platelet aggregation (Plt Aggre), uric acid (UA), creatinine (Cr), blood urea nitrogen (BUN), and C-reactive protein (CRP), whereas IMT was significantly correlated with the levels of Cr, BUN, and CRP. CAVI and IMT were suitable for stratification of the patients. A comparison of hemostatic markers (D-dimer, fibrinogen and Plt Aggre) between the less sclerotic group (group A; CAVI <8.0 and IMT <1.1 mm, n = 26) and the highly sclerotic group (group B; CAVI >8.0 and IMT >1.1 mm, n = 32) revealed that the incidence of thrombosis was significantly higher in group B (18.8%) than in group A (3.8%) and that D-dimer was significantly higher (p < 0.01, Mann-Whitney U test) in group B (0.48 mug/ml, median) than in group A (0.32 mug/ml, median). Moreover, multiple linear regression analyses of CAVI and IMT indicated that D-dimer and age were significant variables. In conclusion, D-dimer is significantly associated with thrombosis in highly atherosclerotic patients.
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