ArticleCell adhesion & migration
Diversity in the molecular and cellular strategies of epithelium-to-mesenchyme transitions: Insights from the neural crest.
Article in Cell adhesion & migration. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 52 citations in OpenAlex.
- Vimentin in Developing Human Adrenal Medulla Cells.Life (Basel, Switzerland) · 2026Article
- The Redox-Adhesion-Exosome (RAX) Hub in Cancer: Lipid Peroxidation-Driven EMT Plasticity and Ferroptosis Defense with HNE/MDA Signaling and Lipidomic Perspectives.Antioxidants (Basel, Switzerland) · 2025Review
- Non-canonical nuclear function of glutaminase cooperates with Wnt signaling to drive EMT during neural crest development.Nature communications · 2025Article
- Endocardial-to-mesenchymal transition underlies cardiac outflow tract septation and bicuspid aortic valve formation in the Syrian hamster model.Scientific reports · 2025Article
- BMP4 regulates differentiation of nestin-positive stem cells into melanocytes.Cellular and molecular life sciences : CMLS · 2025Article
- Single-cell RNA-seq of in vitro expanded cells from cranial neural crest reveals a rare odontogenic sub-population.Cell proliferation · 2024Article
- Pediatric Diffuse Midline Glioma H3K27-Altered: From Developmental Origins to Therapeutic Challenges.Cancers · 2024Review
- Expansion of a neural crest gene signature following ectopic MYCN expression in sympathoadrenal lineage cells in vivo.PloS one · 2024Article
- Polarity and migration of cranial and cardiac neural crest cells: underlying molecular mechanisms and disease implications.Frontiers in cell and developmental biology · 2024Review
- Identification of a differentiation stall in epithelial mesenchymal transition in histone H3-mutant diffuse midline glioma.GigaScience · 2020Article
- Contribution of neural crest-derived stem cells and nasal chondrocytes to articular cartilage regeneration.Cellular and molecular life sciences : CMLS · 2020Review
- Dissection, Culture and Analysis of Primary Cranial Neural Crest Cells from Mouse for the Study of Neural Crest Cell Delamination and Migration.Journal of visualized experiments : JoVE · 2019Article
- From neural crest cells to melanocytes: cellular plasticity during development and beyond.Cellular and molecular life sciences : CMLS · 2019Review
- Investigating epithelial-to-mesenchymal transition with integrated computational and experimental approaches.Physical biology · 2019Review
- Should I stay or should I go? Cadherin function and regulation in the neural crest.Genesis (New York, N.Y. : 2000) · 2017Review
- Modeling Developmental and Tumorigenic Aspects of Trilateral Retinoblastoma via Human Embryonic Stem Cells.Stem cell reports · 2017Article
- A potential inhibitory function of draxin in regulating mouse trunk neural crest migration.In vitro cellular & developmental biology. Animal · 2017Article
- Article
- Epithelial-Mesenchymal Transitions during Neural Crest and Somite Development.Journal of clinical medicine · 2015Review
- Embryonic Chicken Transplantation is a Promising Model for Studying the Invasive Behavior of Melanoma Cells.Frontiers in oncology · 2015Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although epithelial to mesenchymal transitions (EMT) are often viewed as a unique event, they are characterized by a great diversity of cellular processes resulting in strikingly different outcomes. They may be complete or partial, massive or progressive, and lead to the complete disruption of the epithelium or leave it intact. Although the molecular and cellular mechanisms of EMT are being elucidated owing chiefly from studies on transformed epithelial cell lines cultured in vitro or from cancer cells, the basis of the diversity of EMT processes remains poorly understood. Clues can be collected from EMT occuring during embryonic development and which affect equally tissues of ectodermal, endodermal or mesodermal origins. Here, based on our current knowledge of the diversity of processes underlying EMT of neural crest cells in the vertebrate embryo, we propose that the time course and extent of EMT do not depend merely on the identity of the EMT transcriptional regulators and their cellular effectors but rather on the combination of molecular players recruited and on the possible coordination of EMT with other cellular processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.