Evidence map›Paper›PMID 20557039›Full record

ArticleJournal of the American Chemical Society2010

Precise mapping of RNA tertiary structure via nanometer distance measurements with double electron-electron resonance spectroscopy.

Nak-Kyoon Kim, Michael K Bowman, Victoria J DeRose

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

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  14. Site-specific platinum(II) cross-linking in a ribozyme active site.Journal of the American Chemical Society · 2012
    Article
  15. RNA dynamics: perspectives from spin labels.Wiley interdisciplinary reviews. RNA
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nak-Kyoon KimDepartment of Chemistry, Texas A&M University, College Station, Texas 77842, USA.
Michael K Bowman
Victoria J DeRose
University of Alabama · USUniversity of California, Los Angeles · US

Funding

Metal Ion Probes Membrane Protein Structure And FunctionR01GM061904 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI BOWMAN, MICHAEL K. · 2001 to 2009
$2.3M
METAL SITES AND DYNAMICS IN LARGE RNA MOLECULESR01GM058096 · NIGMS · UNIVERSITY OF OREGON · PI DEROSE, VICTORIA J. · 1998 to 2010
$2.2M
NIGMS NIH HHS GM058096NIGMS NIH HHS GM061904NIGMS NIH HHS R01 GM058096NIGMS NIH HHS R01 GM061904
6 · The paper itself

Abstract

Divalent metal (Mg(2+)) ion-dependent folding of the hammerhead ribozyme from Schistosoma mansoni was monitored with double electron-electron resonance (DEER) pulsed electron paramagnetic resonance spectroscopy by measuring nanometer-scale distances between paramagnetic spin-labels attached to the RNA. DEER measurements detect global folding of the ribozyme with excellent agreement between predictions from experimental, modeled, and crystallographic measurements. These measurements demonstrate the use of DEER spectroscopy as a tool for structural analysis of complex RNAs.

Indexed as

ElectronsSpectrum AnalysisAnimalsBase SequenceCrystallography, X-RayMetalsNucleic Acid ConformationRNARNA, CatalyticSchistosoma mansonihammerhead ribozymeMetalsRNARNA, Catalytic

Identifiers

PMID20557039
PMCPMC2908488
OpenAlexW2022725814

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.