ArticleParasitology research2010
Glycosylation of the major polar tube protein of Encephalitozoon cuniculi.
Article in Parasitology research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- NcPTP2, a polar tube protein, interacts with spore wall protein in the parasitic microsporidian Nosema ceranae.Molecular biology reports · 2024Article
- Article
- Germination of Microsporidian Spores: The Known and Unknown.Journal of fungi (Basel, Switzerland) · 2023Review
- Identification and localization of polar tube proteins in the extruded polar tube of the microsporidian Anncaliia algerae.Scientific reports · 2023Article
- The Function and Structure of the Microsporidia Polar Tube.Experientia supplementum (2012) · 2022Article
- Identification and characterization a novel polar tube protein (NbPTP6) from the microsporidian Nosema bombycis.Parasites & vectors · 2020Article
- Invasion of Host Cells by Microsporidia.Frontiers in microbiology · 2020Review
- Renal Microsporidiosis in Pediatric Bone Marrow Transplant Recipients: A Case Series.Turk patoloji dergisi · 2020Article
- An Ultrastructural Study of the Extruded Polar Tube of Anncaliia algerae (Microsporidia).The Journal of eukaryotic microbiology · 2020Article
- Article
- Microsporidia: Obligate Intracellular Pathogens Within the Fungal Kingdom.Microbiology spectrum · 2017Review
- The role of microsporidian polar tube protein 4 (PTP4) in host cell infection.PLoS pathogens · 2017Article
- Reduction and expansion in microsporidian genome evolution: new insights from comparative genomics.Genome biology and evolution · 2013Article
- Microsporidiosis: not just in AIDS patients.Current opinion in infectious diseases · 2011Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
To infect their host cells the Microsporidia use a unique invasion organelle, the polar tube complex. During infection, the organism is injected into the host cell through the hollow polar tube formed during spore germination. Currently, three proteins, PTP1, PTP2, and PTP3 have been identified by immunological and molecular techniques as being components of this structure. Genomic data suggests that Microsporidia are capable of O-linked, but not N-linked glycosylation as a post-translational protein modification. Cells were infected with Encephalitozoon cunicuili, labeled with radioactive mannose or glucosamine, and the polar tube proteins were examined for glycosylation. PTP1 was clearly demonstrated to be mannosylated consistent with 0-glycosylation. In addition, it was evident that several other proteins were mannosylated, but no labeling was seen with glucosamine. The observed post-translational mannosylation of PTP1 may be involved in the functional properties of the polar tube, including its adherence to host cells during penetration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.