Evidence map›Paper›PMID 20554818›Full record

ArticleJournal of clinical microbiology2010

Caught in the act: in vivo development of macrolide resistance to Campylobacter jejuni infection.

J C Lindow, F Poly, D R Tribble, P Guerry, M P Carmolli, S Baqar, C K Porter, K K Pierce, M J Darsley, K S Sadigh and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Lack of homologous protection against Campylobacter jejuni CG8421 in a human challenge model.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Trial
  2. Review
  3. RecurrentInfectious disease reports · 2022
    Article
  4. Update on Campylobacter vaccine development.Human vaccines & immunotherapeutics · 2019
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

J C LindowVaccine Testing Center, University of Vermont College of Medicine, Department of Medicine, Burlington, VT 05405, USA. janet.lindow@uvm.edu
F Poly
D R Tribble
P Guerry
M P Carmolli
S Baqar
C K Porter
K K Pierce
M J Darsley
K S Sadigh
E A Dill
Campylobacter Study Team
B D Kirkpatrick

Funding

WEIGHT MAINTENANCE AND PSYCHOLOGICAL BENEFITS OF EXERCISEM01RR000109 · NCRR · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI DUMAS, JULIE A · 1985 to 2010
$24.3M
NCRR NIH HHS M01 RR000109
6 · The paper itself

Abstract

We report the first instance of macrolide resistance developing in vivo following appropriate antibiotic use in a healthy volunteer as a part of a controlled human infection with Campylobacter jejuni. In vivo development of macrolide resistance may be an important contributor to antibiotic resistance in C. jejuni.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacterial Typing TechniquesCampylobacter InfectionsCampylobacter jejuniDNA, BacterialDNA FingerprintingElectrophoresis, Gel, Pulsed-FieldHealthy VolunteersHumansMacrolidesMaleMicrobial Sensitivity TestsYoung AdultAnti-Bacterial AgentsDNA, BacterialMacrolides

Identifiers

PMID20554818
PMCPMC2916616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.