ArticleSchizophrenia research2010
Frontonasal dysmorphology in bipolar disorder by 3D laser surface imaging and geometric morphometrics: comparisons with schizophrenia.
Article in Schizophrenia research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Article
- Mandibular morphology in schizophrenia patients compared with non-psychiatric controls using digital panoramic radiography: a retrospective cross-sectional study from Istanbul, Türkiye.BMC oral health · 2024Article
- Correlational research on facial and clinical characteristics of adolescents with obsessive-compulsive disorder.BMC psychiatry · 2021Article
- 3D facial phenotyping by biometric sibling matching used in contemporary genomic methodologies.PLoS genetics · 2021Article
- Refining the resolution of craniofacial dysmorphology in bipolar disorder as an index of brain dysmorphogenesis.Psychiatry research · 2020Article
- Enabling Global Clinical Collaborations on Identifiable Patient Data: The Minerva Initiative.Frontiers in genetics · 2019Article
- Facial Genetics: A Brief Overview.Frontiers in genetics · 2018Review
- Translational Genetic Modelling of 3D Craniofacial Dysmorphology: Elaborating the Facial Phenotype of Neurodevelopmental Disorders Through the "Prism" of Schizophrenia.Current behavioral neuroscience reports · 2017Review
- Quantitative Measures of Craniofacial Dysmorphology in a Family Study of Schizophrenia and Bipolar Illness.Schizophrenia bulletin · 2015Article
- Anatomical curve identification.Computational statistics & data analysis · 2015Article
- Craniofacial dysmorphology in 22q11.2 deletion syndrome by 3D laser surface imaging and geometric morphometrics: illuminating the developmental relationship to risk for psychosis.American journal of medical genetics. Part A · 2015Article
- Facial Morphogenesis: Physical and Molecular Interactions Between the Brain and the Face.Current topics in developmental biology · 2015Review
- Sleep-disordered breathing and psychiatric disorders.Current psychiatry reports · 2014Review
- A population-based cross-sectional study of the association between facial morphology and cardiometabolic risk factors in adolescence.BMJ open · 2013Article
- Atypical face shape and genomic structural variants in epilepsy.Brain : a journal of neurology · 2012Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Any developmental relationship between bipolar disorder and schizophrenia engenders continuing debate. As the brain and face emerge in embryological intimacy, brain dysmorphogenesis is accompanied by facial dysmorphogenesis. 3D laser surface imaging was used to capture the facial surface of 13 male and 14 female patients with bipolar disorder in comparison with 61 male and 75 female control subjects and with 37 male and 32 female patients with schizophrenia. Surface images were analysed using geometric morphometrics and 3D visualisations to identify domains of facial shape that distinguish bipolar patients from controls and bipolar patients from those with schizophrenia. Both male and female bipolar patients evidenced significant facial dysmorphology: common to male and female patients was overall facial widening, increased width of nose, narrowing of mouth and upward displacement of the chin; dysmorphology differed between male and female patients for nose length, lip thickness and tragion height. There were few morphological differences in comparison with schizophrenia patients. That dysmorphology of the frontonasal prominences and related facial regions in bipolar disorder is more similar to than different from that found in schizophrenia indicates some common dysmorphogenesis. Bipolar disorder and schizophrenia might reflect similar insult(s) acting over slightly differing time-frames or slightly differing insult(s) acting over a similar time-frame.
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Registered trials
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