ArticleBMC gastroenterology2010
Helicobacter pylori in apparently healthy children aged 0-12 years in urban Kampala, Uganda: a community-based cross sectional survey.
Article in BMC gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Prevalence and associated risk factors of Helicobacter pylori infection in East Africa: a systematic review and meta-analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Pooled it
- Helicobacter pylori Infection Mass Screening for Children and Adolescents: a Systematic Review of Observational Studies.Journal of gastrointestinal cancer · 2021Pooled it
- Breast-feeding and Helicobacter pylori infection: systematic review and meta-analysis.Public health nutrition · 2015Pooled it
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- The high sensitivity and specificity of rapid urease test in diagnosis ofIranian journal of microbiology · 2022Article
- Worldwide Prevalence and Risk Factors ofChildren (Basel, Switzerland) · 2022Review
- Prevalence and factors associated withAfrican health sciences · 2022Article
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- Association ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Assessment of the diagnostic accuracy and relevance of a novel ELISA system developed for seroepidemiologic surveys of Helicobacter pylori infection in African settings.PLoS neglected tropical diseases · 2021Article
- Prevalence ofJournal of tropical medicine · 2021Article
- Prevalence ofAfrican health sciences · 2020Article
- Seroprevalence, risk factors and comorbidities associated withAfrican health sciences · 2019Article
- Infections withWorld journal of gastroenterology · 2019Review
- Prevalence and patient characteristics ofJournal of family medicine and primary care · 2019Article
- Seroprevalence and determinants ofAfrican health sciences · 2019Article
- Prevalence and Risk Factors ofJournal of tropical medicine · 2019Article
- Prevalence and Associated Symptoms ofInterdisciplinary perspectives on infectious diseases · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHelicobacter pylori is one of the most common causes of bacterial infection in human beings. Studies have showed a high prevalence of Helicobacter pylori among people in low-income countries and colonization early in life. A monoclonal antigen test, performed on faeces, HpSA ImmunoCardSTAT, has a high sensitivity, specificity and accuracy and the faecal test can be performed in all ages, also in resource-limited settings. The main objective of this study was to determine the prevalence and factors associated with Helicobacter pylori colonization in apparently healthy children aged 0-12 years in urban Kampala, Uganda.
methodWe tested 427 apparently healthy children, age 0-12 years (211 males, 216 females), in a cross sectional survey for Helicobacter pylori colonization using HpSA ImmunoCardSTAT. A short standardized interview with socio-demographic information and medical history was used to assess risk factors.
resultsThe overall prevalence of Helicobacter pylori in the 427 children was 44.3% (189 out of 427). Early colonization was common, 28.7%, in children younger than 1 year of age. The age specific rates were 46.0% in children age 1- < 3 years, 51.7% in children age 3- < 6 years, 54.8% in children age 6- < 9 years and 40.0% in children age 9- < 12 years. There was a significant difference in prevalence by gender; female 38.5% versus male 49.8% and by type of housing; permanent house 38.5% versus semi-permanent house 48.6%. Congestive living and education level of the female caretaker showed a clear trend for a difference in prevalence. Factors independently associated with Helicobacter pylori colonization included: drugs taken last three months, using a pit latrine, sources of drinking water and wealth index.
conclusionThe prevalence of Helicobacter pylori colonization among urban Ugandan children is high at an early age and increases with age. The impact of Helicobacter pylori colonization on children's health in Uganda needs to be further clarified.
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