ArticleJournal of the American Geriatrics Society2010
Hospitalization in community-dwelling persons with Alzheimer's disease: frequency and causes.
Article in Journal of the American Geriatrics Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
96 citing papers in PubMed, 5 syntheses or guidelines pooled it, 207 citations in OpenAlex.
- Rural and urban differences in quality of dementia care of persons with dementia and caregivers across all domains: a systematic review.BMC health services research · 2023Pooled it
- Hospitalisation rates and predictors in people with dementia: a systematic review and meta-analysis.BMC medicine · 2019Pooled it
- Pooled it
- A systematic review of intervention studies to prevent hospitalizations of community-dwelling older adults with dementia.Medical care · 2015Pooled it
- The Impact of Ambulatory Dementia Care Models on Hospitalization of Persons Living With Dementia: A Systematic Review.Research on agingPooled it
- Trial
- Comparison of evidence-based interventions on outcomes of hospitalized, cognitively impaired older adults.Journal of comparative effectiveness research · 2014Trial
- A feasibility study and pilot randomised trial of a tailored prevention program to reduce falls in older people with mild dementia.BMC geriatrics · 2013Trial
- Care in specialist medical and mental health unit compared with standard care for older people with cognitive impairment admitted to general hospital: randomised controlled trial (NIHR TEAM trial).BMJ (Clinical research ed.) · 2013Trial
- Data-driven subtyping of Alzheimer's emergency presentations using unsupervised machine learning.IBRO neuroscience reports · 2026Article
- Article
- Dementia Caregivers' Preferences for Involvement in Delirium Care During Hospitalization.Journal of the American Geriatrics Society · 2026Article
- Detecting multimorbidity patterns in Alzheimer's disease using unsupervised machine learning: A nationwide emergency department study (2007-2022).Journal of Alzheimer's disease : JAD · 2026Article
- Association of Cognitive Impairments and Alzheimer's Disease and Related Dementias With Hospital and Skilled Nursing Facility Utilization Among Community-Dwelling Older Adults.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Observational
- Article
- Combined and synergistic effects of heat and fine particulate matter on hospitalization among patients with Alzheimer's disease and related dementias.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Predicting hospice eligibility among dementia patients using language models.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- The Effect of Influenza Vaccination on Hospitalization and Mortality Among People With Dementia.Journal of the American Geriatrics Society · 2025Article
- Characteristics and hospitalization of people living with dementia after home healthcare: A nationwide cohort study.Medicine · 2025Observational
- Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesTo examine the rates of and risk factors for acute hospitalization in a prospective cohort of older community-dwelling patients with Alzheimer's disease (AD).
designLongitudinal patient registry.
settingAD research center.
participantsEight hundred twenty-seven older persons with AD. MEASUREMENTS: Acute hospitalization after AD research center visit was determined from a Medicare database. Risk factor variables included demographics, dementia-related, comorbidity and diagnoses and were measured in interviews and according to Medicare data.
resultsOf the 827 eligible patients seen at the ADRC during 1991 to 2006 (median follow-up 3.0 years), 542 (66%) were hospitalized at least once, and 389 (47%) were hospitalized two or more times, with a median of 3 days spent in the hospital per person-year. Leading reasons for admission were syncope or falls (26%), ischemic heart disease (17%), gastrointestinal disease (9%), pneumonia (6%), and delirium (5%). Five significant independent risk factors for hospitalization were higher comorbidity (hazard ratio (HR)=1.87, 95% confidence interval (CI)=1.57-2.23), previous acute hospitalization (HR=1.65, 95% CI=1.37-1.99), older age (HR=1.51, 95% CI=1.26-1.81), male sex (HR=1.27, 95% CI=1.04-1.54), and shorter duration of dementia symptoms (HR=1.26, 95% CI=1.02-1.56). Cumulative risk of hospitalization increased with number of risk factors present at baseline: 38% with zero factors, 57% with one factor, 70% with two or three factors, and 85% with four or five factors (P(trend) <.001).
conclusionIn a community-dwelling population with generally mild AD, hospitalization is frequent, occurring in two-thirds of participants over a median follow-up time of 3 years. With these results, clinicians may be able to identify dementia patients at high risk for hospitalization.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.