ArticleLasers in medical science2010
Laser light combined with a photosensitizer may eliminate methicillin-resistant strains of Staphylococcus aureus.
Article in Lasers in medical science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 42 citations in OpenAlex.
- A novel chlorine derivative ShengTaiBuFen mediated photodynamic therapy on a mouse wound model infected with methicillin-resistant Staphylococcus aureus.Lasers in medical science · 2025Article
- Photodynamic Antimicrobial Activity of a Novel 5,10,15,20-Tetrakis (4-Ethylphenyl) Porphyrin against Clinically Important Bacteria.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Use of photodynamic therapy and photobiomodulation as alternatives for microbial control on clinical and subclinical mastitis in sheep.Lasers in medical science · 2022Article
- Efficacy and safety of photodynamic therapy with RLP068 for diabetic foot ulcers: a review of the literature and clinical experience.Drugs in context · 2020Review
- Nonconventional Therapeutics againstMicrobiology spectrum · 2018Article
- Antimicrobial Photodynamic Therapy: An Effective Alternative Approach to Control Bacterial Infections.Journal of lasers in medical sciences · 2018Review
- Photodynamic therapy controls of Staphylococcus aureus intradermal infection in mice.Lasers in medical science · 2017Article
- Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections.Journal of clinical and translational research · 2015Review
- In vitro effectiveness of antimicrobial photodynamic therapy (APDT) using a 660 nm laser and malachite green dye in Staphylococcus aureus biofilms arranged on compact and cancellous bone specimens.Lasers in medical science · 2014Article
- Multiresistant strains are as susceptible to photodynamic inactivation as their naïve counterparts: protoporphyrin IX-mediated photoinactivation reveals differences between methicillin-resistant and methicillin-sensitive Staphylococcus aureus strains.Photomedicine and laser surgery · 2014Article
- A new preclinical approach for treating chronic osteomyelitis induced by Staphylococcus aureus: in vitro and in vivo study on photodynamic antimicrobial therapy (PAmT).Lasers in medical science · 2014Article
- Can biowarfare agents be defeated with light?Virulence · 2013Review
- Antimicrobial photodynamic therapy for methicillin-resistant Staphylococcus aureus infection.BioMed research international · 2013Review
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of hospital acquired infection throughout the world especially in wound and burn infections, pneumonia, septicaemia and endocarditis. We describe the effect of a HeNe laser in combination with a TBO dye on the viability of MRSA. A total of 34 isolates of S. aureus were obtained from 100 patients suffering from burns or wounds and from the nasal vestibulum of medical and nonmedical staff as carriers; eight isolates were methicillin-resistant. The isolates were exposed for 5, 10 and 15 min to a HeNe laser at a wavelength of 632.8 nm and 7.5 mW output power in the presence of 50 microg/ml toluidune blue O photosensitizer. The viable count was substantially decreased as determined by the plate count method for the three exposure times, with 100% killing with the 15-min exposure time. No significant effect was observed on MRSA isolates exposed to the laser alone. So MRSA was completely eradicated following 15 min exposure to a 632.8-nm HeNe laser in the presence of 50 microg/ml toluidune blue O photosensitizer under in vitro conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.