Evidence map›Paper›PMID 20552287›Full record

ArticleMolecular imaging and biology2011

Motion-artifact-free in vivo imaging utilizing narcotized avian embryos in ovo.

Alexander Heidrich, Lydia Würbach, Thomas Opfermann, Hans Peter Saluz

Abstract read
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In one paragraph

Article in Molecular imaging and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  4. Review
  5. Longitudinal volumetric analysis ofFrontiers in veterinary science · 2024
    Article
  6. Different narcotic gases and concentrations for immobilization of ostrich embryos forExperimental biology and medicine (Maywood, N.J.) · 2024
    Article
  7. Article
  8. Article
  9. Article
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  12. Article
  13. Quantitative three-dimensional imaging of live avian embryonic morphogenesis via micro-computed tomography.Developmental dynamics : an official publication of the American Association of Anatomists · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexander HeidrichDepartment of Cell and Molecular Biology, Leibniz Institute for Natural Product Research and Infection Biology (Hans Knoell Institute), Beutenbergstrasse 11a, 07745 Jena, Germany.
Lydia Würbach
Thomas Opfermann
Hans Peter Saluz
Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) · DELeibniz Association · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe chick embryo in ovo is a well-accessible and economical in vivo model, but its use in molecular imaging has been limited because of motion artifacts on resulting images. The purpose of this study was to develop a method using narcotics to inhibit motility and to perform motion-artifact-free imaging of living chick embryos in ovo. PROCEDURES: Chick embryos in ovo were narcotized using three different narcotics: isoflurane, 2,2,2-tribromoethanol, and urethane/α-chloralose. Narcotized embryos were imaged using micro-computed tomography (microCT) at days 10-18 of incubation, and the resulting images were analyzed for reduction of motion artifacts.

resultsAll three anesthetics could be used for anesthetizing living chick embryos in ovo thus allowing the acquisition of motion-artifact-free images.

conclusionsOur experiments revealed that isoflurane is the best-suited narcotic for single and repeated applications to image living chick embryos in ovo.

Indexed as

ArtifactsMotionAnesthesiaAnestheticsAnimalsChick EmbryoChickensChloraloseEthanolIsofluraneNarcoticsTomography, X-Ray ComputedUrethaneAnestheticsChloraloseEthanolIsofluraneNarcoticstribromoethanolUrethane

Identifiers

PMID20552287
OpenAlexW2044248042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.