ReviewCellular and molecular life sciences : CMLS2010
Sexual reproduction in the Candida clade: cryptic cycles, diverse mechanisms, and alternative functions.
Review in Cellular and molecular life sciences : CMLS, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Mating type and genotyping ofIranian journal of microbiology · 2026Article
- Exploring the Biology, Virulence, and General Aspects ofInfection and drug resistance · 2024Review
- What IsMicroorganisms · 2022Review
- Genomic Approaches to Antifungal Drug Target Identification and Validation.Annual review of microbiology · 2022Review
- Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets.Nature communications · 2021Article
- Extreme diversification driven by parallel events of massive loss of heterozygosity in the hybrid lineage of Candida albicans.Genetics · 2021Article
- Genomic evidence for a hybrid origin of the yeast opportunistic pathogen Candida albicans.BMC biology · 2020Article
- New approaches in bioprocess-control: Consortium guidance by synthetic cell-cell communication based on fungal pheromones.Engineering in life sciences · 2018Review
- Parasex Generates Phenotypic DiversityGenetics · 2017Article
- A novel function for Hog1 stress-activated protein kinase in controlling white-opaque switching and mating in Candida albicans.Eukaryotic cell · 2014Article
- Rapid mechanisms for generating genome diversity: whole ploidy shifts, aneuploidy, and loss of heterozygosity.Cold Spring Harbor perspectives in medicine · 2014Review
- Parasexuality and ploidy change in Candida tropicalis.Eukaryotic cell · 2013Article
- MTL-independent phenotypic switching in Candida tropicalis and a dual role for Wor1 in regulating switching and filamentation.PLoS genetics · 2013Article
- Epidemiology and changes in patient-related factors from 1997 to 2009 in clinical yeast isolates related to dermatology, gynaecology, and paediatrics.International journal of microbiology · 2013Article
- Allelic sequence heterozygosity in single Giardia parasites.BMC microbiology · 2012Article
- Does stress induce (para)sex? Implications for Candida albicans evolution.Trends in genetics : TIG · 2012Article
- Discovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Defining pheromone-receptor signaling in Candida albicans and related asexual Candida species.Molecular biology of the cell · 2011Article
- Fungal mating pheromones: choreographing the dating game.Fungal genetics and biology : FG & B · 2011Review
- Interspecies pheromone signaling promotes biofilm formation and same-sex mating in Candida albicans.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
To have sex, or not to have sex, is a question posed by many microorganisms. In favor of a sexual lifestyle is the associated rearrangement of genetic material that confers potential fitness advantages, including resistance to antimicrobial agents. The asexual lifestyle also has benefits, as it preserves complex combinations of genes that may be optimal for pathogenesis. For this reason, it was thought that several pathogenic fungi favored strictly asexual modes of reproduction. Recent approaches using genome sequencing, population analysis, and experimental techniques have now revised this simplistic picture. It is now apparent that many pathogenic fungi have retained the ability to undergo sexual reproduction, although reproduction is primarily clonal in origin. In this review, we highlight the current understanding of sexual programs in the Candida clade of species. We also examine evidence that sexual-related processes can be used for functions in addition to mating and recombination in these organisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.