ArticleRadiology2010
Locally recurrent prostate cancer after external beam radiation therapy: diagnostic performance of 1.5-T endorectal MR imaging and MR spectroscopic imaging for detection.
Article in Radiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Functional Magnetic Resonance Imaging in the Diagnosis of Locally Recurrent Prostate Cancer: Are All Pulse Sequences Helpful?Korean journal of radiologyPooled it
- The Role of Salvage Radical Prostatectomy in Patients with Radiation-Resistant Prostate Cancer.Cancers · 2023Review
- Prediction of prostate cancer recurrence after radiation therapy using multiparametric magnetic resonance imaging and spectroscopy: assessment of prognostic factors on pretreatment imaging.Quantitative imaging in medicine and surgery · 2022Article
- Magnetic resonance biomarkers in radiation oncology: The report of AAPM Task Group 294.Medical physics · 2021Article
- Clinical application and progress of quantitative functional magnetic resonance imaging in prostate cancer.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Article
- Effect of androgen deprivation and radiation therapy on MRI fiber tractography in prostate cancer: can we assess treatment response on imaging?The British journal of radiology · 2019Article
- The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective.International journal of radiation oncology, biology, physics · 2018Review
- Two-years Postradiotherapy Biopsies: Lessons from MRC RT01 Trial.European urology · 2018Article
- Salvage Low Dose Rate Brachytherapy For Recurrent Prostate Cancer After External Beam Radiotherapy: Results From A Single Institution With Focus On Toxicity And Functional Outcomes.Clinical Medicine Insights. Oncology · 2017Article
- Anatomical Patterns of Recurrence Following Biochemical Relapse in the Dose Escalation Era of External Beam Radiotherapy for Prostate Cancer.The Journal of urology · 2015Article
- Pictorial review. Diagnosis of recurrent prostate cancer and its mimics at multiparametric prostate MRI.The British journal of radiology · 2015Review
- Multiparametric MRI for detection of radiorecurrent prostate cancer: added value of apparent diffusion coefficient maps and dynamic contrast-enhanced images.Prostate cancer and prostatic diseases · 2015Article
- A Domain Constrained Deformable (DoCD) Model for Co-registration of Pre- and Post-Radiated Prostate MRI.Neurocomputing · 2014Article
- Targeted radiotherapy with gold nanoparticles: current status and future perspectives.Nanomedicine (London, England) · 2014Review
- [Prostate cancer].Der Radiologe · 2014Article
- Prostate cancer and its mimics at multiparametric prostate MRI.The British journal of radiology · 2014Review
- Multiparametric magnetic resonance imaging in the management and diagnosis of prostate cancer: current applications and strategies.Current urology reports · 2014Review
- A paradigm shift from anatomic to functional and molecular imaging in the detection of recurrent prostate cancer.Future oncology (London, England) · 2014Review
- The role of metabolic imaging in radiation therapy of prostate cancer.NMR in biomedicine · 2014Review
- Multiparametric MRI for recurrent prostate cancer post radical prostatectomy and postradiation therapy.BioMed research international · 2014Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo determine if performing magnetic resonance (MR) spectroscopic imaging, compared with performing T2-weighted MR imaging alone, improves the detection of locally recurrent prostate cancer after definitive external beam radiation therapy. MATERIALS AND
methodsThis retrospective single-institution study was approved by the committee on human research, with a waiver of informed consent, and was compliant with HIPAA requirements. Sixty-four men who underwent endorectal MR imaging, MR spectroscopic imaging, and transrectal ultrasonographically guided biopsy for suspected local recurrence of prostate cancer after definitive external beam radiation therapy were retrospectively identified. Thirty-three patients had also received androgen therapy. Recurrent cancer was determined to be present or absent in the left and right sides of the prostate at T2-weighted MR imaging and MR spectroscopic imaging by a radiologist and a spectroscopist, respectively. Area under the receiver operating characteristic curve (A(Z)) was calculated for T2-weighted MR imaging alone and combined T2-weighted MR imaging and MR spectroscopic imaging by using generalized estimating equations and by using biopsy results as the reference standard.
resultsRecurrent prostate cancer was identified at biopsy in 37 (58%) of the 64 men. Recurrence was unilateral in 28 patients and bilateral in nine (total of 46 affected prostate sides). A(Z) analysis revealed that use of combined T2-weighted MR imaging and MR spectroscopic imaging (A(Z) = 0.79), as compared with T2-weighted MR imaging alone (A(Z) = 0.67), significantly improved the detection of local recurrence (P = .001).
conclusionThe addition of MR spectroscopic imaging to T2-weighted MR imaging significantly improves the diagnostic accuracy of endorectal MR imaging in the detection of locally recurrent prostate cancer after definitive external beam radiation therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.