ArticleCritical care (London, England)2010
Model of end stage liver disease (MELD) score greater than 23 predicts length of stay in the ICU but not mortality in liver transplant recipients.
Article in Critical care (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Clinical outcomes of early versus standard liver transplantation in patients with alcohol-related liver disease: a meta-analysis.Langenbeck's archives of surgery · 2026Pooled it
- Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review.Critical care (London, England) · 2011Pooled it
- Impact of early reoperation on graft survival after liver transplantation: Univariate and multivariate analysis.Clinical transplantation · 2018Trial
- Association of Pre-Transplant Tyrosine Kinase Inhibitor Therapy With Tumor Response and Survival in Hepatocellular Carcinoma: A 10-Year Retrospective Cohort Study of 427 Patients.World journal of surgery · 2026Observational
- Development and Internal Validation of a Web-Based Dynamic Nomogram for Dynamic Risk Stratification of Early Bacterial Infection in Liver Transplant Recipients.Annals of transplantation · 2026Article
- Developing a Novel Artificial Intelligence Framework to Measure the Balance of Clinical Versus Nonclinical Influences on Posthepatectomy Length of Stay.Annals of surgical oncology · 2025Article
- Impact of Blood Products Transfusion on Patients in the Immediate Post-Lung Transplant Period: A Cohort Study.Annals of transplantation · 2024Article
- Living-Donor Liver Transplantation for Hepatocellular Carcinoma: Impact of the MELD Score and Predictive Value of NLR on Survival.Current oncology (Toronto, Ont.) · 2022Article
- A simple CD4+ T cells to FIB-4 ratio for evaluating prognosis of BCLC-B hepatocellular carcinoma: a retrospective cohort study.BMC cancer · 2022Article
- Changes in the allocation policy for deceased donor livers in Korea: perspectives from anesthesiologists.Anesthesia and pain medicine · 2021Article
- Outcomes of hemi- versus whole liver transplantation in patients from mainland china with high model for end-stage liver disease scores: a matched analysis.BMC surgery · 2020Article
- Delta MELD as a predictor of early outcome in adult-to-adult living donor liver transplantation.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Article
- Observational
- High MELD score and extended operating time predict prolonged initial ICU stay after liver transplantation and influence the outcome.PloS one · 2017Article
- Is MELD score failing patients with liver disease and hepatorenal syndrome?World journal of hepatology · 2016Article
- Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population.Journal of transplantation · 2016Article
- Article
- Postoperative resource utilization and survival among liver transplant recipients with Model for End-stage Liver Disease score ≥ 40: A retrospective cohort study.Canadian journal of gastroenterology & hepatology · 2015Article
- Hepatosplanchnic circulation in cirrhosis and sepsis.World journal of gastroenterology · 2015Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe impact of model of end stage liver disease (MELD) score on postoperative morbidity and mortality is still elusive, especially for high MELD. There are reports of poorer patient outcome in transplant candidates with high MELD score, others though report no influence of MELD score on outcome and survival.
methodsWe retrospectively analyzed data of 144 consecutive liver transplant recipients over a 72-month period in our transplant unit, from January 2003 until December 2008 and performed uni- and multivariate analysis for morbidity and mortality, in particular to define the influence of MELD to these parameters.
resultsThis study identified MELD score greater than 23 as an independent risk factor of morbidity represented by intensive care unit (ICU) stay longer than 10 days (odds ratio 7.0) but in contrast had no negative impact on mortality. Furthermore, we identified transfusion of more than 7 units of red blood cells as independent risk factor for mortality (hazard ratio 7.6) and for prolonged ICU stay (odds ratio [OR] 7.8) together with transfusion of more than 10 units of fresh frozen plasma (OR 11.6). Postoperative renal failure is a strong predictor of morbidity (OR 7.9) and postoperative renal replacement therapy was highly associated with increased mortality (hazard ratio 6.8), as was hepato renal syndrome prior to transplantation (hazard ratio 13.2).
conclusionsThis study identified MELD score greater than 23 as an independent risk factor of morbidity represented by ICU stay longer than 10 days but in contrast had no negative impact on mortality. This finding supports the transplantation of patients with high MELD score but only with knowledge of increased morbidity.
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