Evidence map›Paper›PMID 20549555›Full record

ReviewAngiogenesis2010

Molecular ultrasound assessment of tumor angiogenesis.

Nirupama Deshpande, Marybeth A Pysz, Jürgen K Willmann

Open access · greenAbstract readReview
In one paragraph

Review in Angiogenesis, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 83 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  7. Review
  8. Article
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  13. Ultrasound Molecular Imaging With BR55 in Patients With Breast and Ovarian Lesions: First-in-Human Results.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017
    Article
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nirupama DeshpandeDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University School of Medicine, 300 Pasteur Drive, Room H1307, Stanford, CA, USA.
Marybeth A Pysz
Jürgen K Willmann
Stanford University · US

Funding

Stanford Molecular Imaging Scholars - SMISR25CA118681 · NCI · STANFORD UNIVERSITY · PI LEVIN, CRAIG S · 2006 to 2015
$5.0M
Early Detection of Pancreatic Cancer with Targeted Contrast-enhanced UltrasoundR21CA139279 · NCI · STANFORD UNIVERSITY · PI WILLMANN, JUERGEN KARL · 2009 to 2010
$388k
NCI NIH HHS R21 CA139279NCI NIH HHS R21CA139279NCI NIH HHS R25 CA11868NCI NIH HHS R25 CA118681
6 · The paper itself

Abstract

Angiogenesis, the growth of new blood vessels, plays a critical role in progression of tumor growth and metastasis, making it an attractive target for both cancer imaging and therapy. Several molecular markers, including those that are involved in the angiogenesis signaling pathway and those unique to tumor angiogenic vessels, have been identified and can be used as targets for molecular imaging of cancer. With the introduction of ultrasound contrast agents that can be targeted to those molecular markers, targeted contrast-enhanced ultrasound (molecular ultrasound) imaging has become an attractive imaging modality to non-invasively assess tumor angiogenesis at the molecular level. The advantages of molecular ultrasound imaging such as high temporal and spatial resolution, non-invasiveness, real-time imaging, relatively low cost, lack of ionizing irradiation and wide availability among the imaging community will further expand its roles in cancer imaging and drug development both in preclinical research and future clinical applications.

Indexed as

UltrasonicsAnimalsBiomarkers, TumorHumansMolecular ImagingNeoplasmsNeovascularization, PathologicUltrasonographyBiomarkers, Tumor

Identifiers

PMID20549555
PMCPMC3140404
OpenAlexW2047628239

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.