ArticleDevelopment genes and evolution2010
Structure of the central nervous system of a juvenile acoel, Symsagittifera roscoffensis.
Article in Development genes and evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32 citing papers in PubMed.
- Article
- Sensory discrimination of chemical and temperature stimuli in the acoel Symsagittifera roscoffensis.PloS one · 2025Article
- Ultrastructural analysis and 3D reconstruction of the frontal sensory-glandular complex and its neural projections in the platyhelminth Macrostomum lignano.Cell and tissue research · 2024Article
- Evolution of glial cells: a non-bilaterian perspective.Neural development · 2024Review
- The Acoel nervous system: morphology and development.Neural development · 2024Review
- Structure of putative epidermal sensory receptors in an acoel flatworm, Praesagittifera naikaiensis.Cell and tissue research · 2024Article
- Articulating the "stem cell niche" paradigm through the lens of non-model aquatic invertebrates.BMC biology · 2022Review
- Acoel Single-Cell Transcriptomics: Cell Type Analysis of a Deep Branching Bilaterian.Molecular biology and evolution · 2021Article
- Neural architecture and regeneration in the acoelProceedings. Biological sciences · 2020Article
- Evolution of Neuroglia.Advances in experimental medicine and biology · 2019Review
- Anesthetic agent etiomidate induces apoptosis in N2a brain tumor cell line.Molecular medicine reports · 2018Article
- SALMFamide2 and serotonin immunoreactivity in the nervous system of some acoels (Xenacoelomorpha).Journal of morphology · 2018Article
- Physiology of Astroglia.Physiological reviews · 2018Review
- Article
- Stratification of astrocytes in healthy and diseased brain.Brain pathology (Zurich, Switzerland) · 2017Article
- The Diversity of Spine Synapses in Animals.Neuromolecular medicine · 2016Review
- Gliocyte and synapse analyses in cerebral ganglia of the Chinese mitten crab, Eriocheir sinensis: ultrastructural study.European journal of histochemistry : EJH · 2016Article
- Genealogical correspondence of a forebrain centre implies an executive brain in the protostome-deuterostome bilaterian ancestor.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- Xenacoelomorpha: a case of independent nervous system centralization?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- Functional brain regeneration in the acoel worm Symsagittifera roscoffensis.Biology open · 2015Article
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4 authors.
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Abstract
The neuroarchitecture of Acoela has been at the center of morphological debates. Some authors, using immunochemical tools, suggest that the nervous system in Acoela is organized as a commissural brain that bears little resemblance to the central, ganglionic type brain of other flatworms, and bilaterians in general. Others, who used histological staining on paraffin sections, conclude that it is a compact structure (an endonal brain; e.g., Raikova 2004; von Graff 1891; Delage Arch Zool Exp Gén 4:109-144, 1886). To address this question with modern tools, we have obtained images from serial transmission electron microscopic sections of the entire hatchling of Symsagittifera roscoffensis. In addition, we obtained data from wholemounts of hatchlings labeled with markers for serotonin and tyrosinated tubulin. Our data show that the central nervous system of a juvenile S. roscoffensis consists of an anterior compact brain, formed by a dense, bilobed mass of neuronal cell bodies surrounding a central neuropile. The neuropile flanks the median statocyst and contains several types of neurites, classified according to their types of synaptic vesicles. The neuropile issues three pairs of nerve cords that run at different dorso-ventral positions along the whole length of the body. Neuronal cell bodies flank the cords, and neuromuscular synapses are abundant. The TEM analysis also reveals different classes of peripheral sensory neurons and provides valuable information about the spatial relationships between neurites and other cell types within the brain and nerve cords. We conclude that the acoel S. roscoffensis has a central brain that is comparable in size and architecture to the brain of other (rhabditophoran) flatworms.
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