ReviewPediatric surgery international2010
Review of genetic factors in intestinal malrotation.
Review in Pediatric surgery international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 112 citations in OpenAlex.
- Adenocarcinoma of the Duodenojejunal Flexure in a Patient With Intestinal Nonrotation.ACG case reports journal · 2026Article
- Article
- Genetic sequencing of children with malrotation and midgut volvulus: A cross-sectional study.JPGN reports · 2026Article
- Management of midgut volvulus in an incomplete common mesentery in a 17-year-old patient: a case report and literature review.International journal of surgery case reports · 2026Article
- Midgut malrotation with volvulus and appendicular agenesis in a young adult woman: a rare case report.International journal of surgery case reports · 2026Article
- Rare variants in TTC7A, ROCK2 and LIMK2 suggest a role for the ROCK-signaling pathway in isolated intestinal malrotation.Pediatric surgery international · 2026Article
- Incomplete reversed midgut rotation with 540° volvulus in an adult: a case report.International journal of surgery case reports · 2026Article
- Clinical characteristics and surgical management of congenital mesenteric defects in children: a 10-year retrospective case series.BMC surgery · 2026Article
- Immunohistochemical detection of putative pathogenetic factors in adhesions of infants: a pilot study.European journal of histochemistry : EJH · 2026Article
- Embryological Basis and Genetic Considerations of Right Lumbar Undescended Caecum with Paracaecal Appendix and Aberrant Vascular Supply.Acta medica Lituanica · 2026Article
- Midgut protrusion, rotation, and retraction induced by temporal alteration in differential growth.Biomechanics and modeling in mechanobiology · 2025Article
- Entirely Right-Sided Colon: A Case Report.Cureus · 2025Article
- Delayed presentation of midgut volvulus in 70-year-old patient: A case report.Radiology case reports · 2025Article
- Adult Acute Appendicitis Complicated by Intestinal Malrotation: A Case Analysis.The American journal of case reports · 2025Article
- Torsion of the wandering spleen with intestinal obstruction.Clinical journal of gastroenterology · 2025Article
- Syndromic variants of biliary atresia.World journal of pediatric surgery · 2025Review
- Laparoscopic resection of a descending colon tumor with right-sided fixation of the sigmoid colon: a case report.Surgical case reports · 2024Article
- Incidentally discovered intestinal malrotation during evaluation for blunt abdominal trauma: A case report.International journal of surgery case reports · 2024Article
- Developmental regulation of cellular metabolism is required for intestinal elongation and rotation.Development (Cambridge, England) · 2024Article
- Molecular Pathways and Animal Models of Defects in Situs.Advances in experimental medicine and biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Intestinal malrotation is well covered in the surgical literature from the point of view of operative management, but few reviews to date have attempted to provide a comprehensive examination of the topic from the point of view of aetiology, in particular genetic aetiology. Following a brief overview of molecular embryology of midgut rotation, we present in this article instances of and case reports and case series of intestinal malrotation in which a genetic aetiology is likely. Autosomal dominant, autosomal recessive, X-linked and chromosomal forms of the disorder are represented. Most occur in syndromic form, that is to say, in association with other malformations. In many instances, recognition of a specific syndrome is possible, one of several examples discussed being the recently described association of intestinal malrotation with alveolar capillary dysplasia, due to mutations in the forkhead box transcription factor FOXF1. New advances in sequencing technology mean that the identification of the genes mutated in these disorders is more accessible than ever, and paediatric surgeons are encouraged to refer to their colleagues in clinical genetics where a genetic aetiology seems likely.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.