Evidence map›Paper›PMID 20549482›Full record

ArticleDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2010

[Principles of skin pigmentation. Biochemistry and regulation of melanogenesis].

M Brenner, C Berking

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. [Topical treatment of pigmentation disorders with cosmetic and pharmaceutical agents].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2020
    Review
  3. Antioxidants (Basel, Switzerland) · 2020
    Article
  4. Article
  5. Antioxidative and Antimelanogenesis Effect ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

M BrennerKlinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Duetschland. michaela.brenner@med.uni-muenchen.de
C Berking
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin pigmentation is highly determined by genetic factors and so far more than 150 genes have been identified that affect skin color either directly or indirectly. The production of eu- and pheomelanin in melanosomes results from the complex interaction between melanogenic regulators in melanocytes and factors derived from keratinocytes and fibroblasts. Besides genetic determination, pigmentation depends on environmental and endocrine factors that modulate the amount, type and distribution of melanins in the skin. Understanding the intrinsic mechanisms of melanogenesis is the basis for modifications of skin pigmentation which are of great interest pharmaceutically and cosmeceutically.

Indexed as

Models, BiologicalAnimalsGene Expression RegulationHumansMelaninsMelanosomesSignal TransductionSkin PigmentationMelanins

Identifiers

PMID20549482
OpenAlexW126249114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.