ReviewCurrent psychiatry reports2010
Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies.
Review in Current psychiatry reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 181 citations in OpenAlex.
- Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.Biological psychiatry · 2022Pooled it
- The Association Between Genetic Variants in the Dopaminergic System and Posttraumatic Stress Disorder: A Meta-Analysis.Medicine · 2016Pooled it
- Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans.Journal of affective disorders · 2015Pooled it
- Genome Editing Dilemma: Navigating Dual-Use Potential and Charting the Path Forward.Journal of bioethical inquiry · 2025Article
- Interactions of the CSF3R polymorphism and early stress on future orientation: evidence for the differential model of stress-related growth.Epidemiology and psychiatric sciences · 2024Article
- Single Prolonged Stress Decreases the Level of Adult Hippocampal Neurogenesis in C57BL/6, but Not in House Mice.Current issues in molecular biology · 2023Article
- Post-Traumatic Stress Disorder, Major Depressive Disorder, and Wildfires: A Fifth-Year Postdisaster Evaluation among Residents of Fort McMurray.International journal of environmental research and public health · 2022Article
- A narrative review of the epigenetics of post-traumatic stress disorder and post-traumatic stress disorder treatment.Frontiers in psychiatry · 2022Review
- CyberGenomics: Application of Behavioral Genetics in Cybersecurity.Behavioral sciences (Basel, Switzerland) · 2021Review
- From genetics to systems biology of stress-related mental disorders.Neurobiology of stress · 2021Article
- Disentangling sex differences in the shared genetic architecture of posttraumatic stress disorder, traumatic experiences, and social support with body size and composition.Neurobiology of stress · 2021Article
- PTSD: Past, present and future implications for China.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2021Review
- Myelination defects in the medial prefrontal cortex of Fkbp5 knockout mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021Article
- Using Monozygotic Twins to Dissect Common Genes in Posttraumatic Stress Disorder and Migraine.Frontiers in neuroscience · 2021Article
- Neurophysiology and Psychopathology Underlying PTSD and Recent Insights into the PTSD Therapies-A Comprehensive Review.Journal of clinical medicine · 2020Review
- Exploring the impact of trauma type and extent of exposure on posttraumatic alterations in 5-HT1A expression.Translational psychiatry · 2020Review
- Bioethical issues in genome editing by CRISPR-Cas9 technology.Turkish journal of biology = Turk biyoloji dergisi · 2020Article
- A review of epigenetic contributions to post-traumatic stress disorder .Dialogues in clinical neuroscience · 2019Review
- The Interaction Between Chronic Pain and PTSD.Current pain and headache reports · 2019Review
- Cell type-specific gene expression patterns associated with posttraumatic stress disorder in World Trade Center responders.Translational psychiatry · 2019Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Post-traumatic stress disorder (PTSD) is a prevalent, disabling anxiety disorder that constitutes a major health care burden. Despite evidence supporting a genetic predisposition to PTSD, the precise genetic loci remain unclear. Herein we review the current state and limitations of genetic research on PTSD. Although recent years have seen an exponential increase in the number of studies examining the influence of candidate genes on PTSD diagnosis and symptomatology, most studies have been characterized by relatively low rates of PTSD, with apparent inconsistencies in gene associations linked to marked differences in methodology. We further discuss how current advances in the genetics field can be applied to studies of PTSD, emphasizing the need to adapt a genome-wide approach that facilitates discovery rather than hypothesis testing. Genome-wide association studies offer the best opportunity to identify novel "true" risk variants for the disorder that in turn has the potential to inform our understanding of PTSD etiology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.