SynthesisThe international journal of cardiovascular imaging2011
Prognostic value of absence or presence of coronary artery disease determined by 64-slice computed tomography coronary angiography a systematic review and meta-analysis.
Synthesis in The international journal of cardiovascular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementing Myocardial Computed Tomographic Perfusion in a Community Hospital Setting
The Safety, Feasibility and Accuracy of Dynamic Computed Tomography Myocardial Perfusion Imaging for Detection of Coronary Artery Disease
The Role of Computed Tomography-Derived Fractional Flow Reserve (CT-FFR) and Myocardial Computed Tomographic Perfusion (CTP) in Patients Presenting With Chest Discomfort
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Characteristics of high-risk coronary plaques identified by computed tomographic angiography and associated prognosis: a systematic review and meta-analysis.European heart journal. Cardiovascular Imaging · 2016Pooled it
- AI-assisted CCTA: supporting diagnosis across the CAD spectrum.The international journal of cardiovascular imaging · 2025Article
- Temporal Relationship-Aware Treadmill Exercise Test Analysis Network for Coronary Artery Disease Diagnosis.Sensors (Basel, Switzerland) · 2024Article
- Prognostic Value of Standard Coronary Computed Tomography Angiography Reporting System (CAD-RADS).The Indian journal of radiology & imaging · 2021Article
- Improving CT-Derived Fractional Flow Reserve Analysis: A Quality Improvement Initiative.Cureus · 2020Article
- Prognostic value of normal and non-obstructive coronary artery disease based on CT angiography findings. A 12 month follow up study.Journal of cardiovascular and thoracic research · 2019Article
- Implication of coronary CT angiography combined with four-dimensional speckle tracking echocardiography for predicting major adverse cardiac events.The international journal of cardiovascular imaging · 2018Observational
- Long-term prognostic value of coronary artery calcium scanning, coronary computed tomographic angiography and stress myocardial perfusion imaging in patients with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Article
- The characteristics of coronary stenosis in 11,267 patients from Southwest China: a retrospective study.Journal of thrombosis and thrombolysis · 2018Article
- Long-term prognostic performance of low-dose coronary computed tomography angiography with prospective electrocardiogram triggering.European radiology · 2017Observational
- Influence of Cardiovascular Risk Factors on the Prevalence of Coronary Atherosclerosis in Patients with Angiographically Normal Coronary Arteries.Academic radiology · 2017Article
- Stress MPI, coronary CTA, and multimodality for subsequent risk analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- How should CT coronary angiography be integrated into the management of patients with chest pain and how does this affect outcomes?European heart journal. Quality of care & clinical outcomes · 2016Article
- Coronary CT Angiography as a Diagnostic and Prognostic Tool: Perspectives from the SCOT-HEART Trial.Current cardiology reports · 2016Review
- Coronary computed tomography angiography for the assessment of chest pain: current status and future directions.The international journal of cardiovascular imaging · 2015Review
- Nonalcoholic Fatty Liver Disease Is Associated with the Presence and Morphology of Subclinical Coronary Atherosclerosis.Yonsei medical journal · 2015Article
- New insights from major prospective cohort studies with cardiac CT.Current cardiology reports · 2015Review
- Noninvasive physiologic assessment of coronary stenoses using cardiac CT.BioMed research international · 2015Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To determine via a meta-analysis the prognostic value of 64-slice computed tomography angiography (CTA) by quantifying risk of major adverse cardiac events (MACE) in different patient groups classified according to CT angiographic findings. A systematic literature search and meta-analyses was conducted on 10 studies examining stable, symptomatic and intermediate risk patients by 64-slice CTA. Patients were followed up for a mean of 21 month. Patient groups with CT-angiographic non-obstructive (stenosis <50% of luminal narrowing) or obstructive (stenosis ≥50% of luminal narrowing) CAD were compared to those having normal angiography without CAD. MACE (cardiac death, non-fatal myocardial infarction and revascularization) numbers were used to calculate odds ratios (OR) with 95% confidence interval (CI) in each group. Ten studies including 5,675 patients were eligible for meta-analysis. The cumulative MACE rate over 21 months were 0.5% in patients with normal CTA, 3.5% in non-obstructive CAD and 16% in obstructive CAD. Compared to normal CTA, non-obstructive CAD was associated with significant increased risk of MACE with OR=6.68 (3.01-14.82 CI 95%), P=0.0001. Obstructive CAD was associated with further significant increased risk of MACE with OR=41.19 (22.56-75.18, CI 95%), P=0.0001. The studies were homogenous, P-value >0.05 for heterogeneity. 64-slice CTA is able to differentiate low-risk from high-risk patients with suspected or known CAD. Absence of CAD predicts excellent prognosis, while obstructive CAD is associated with markedly increased risk of MACE.
Indexed as
Identifiers
20549366What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.