Evidence map›Paper›PMID 20549251›Full record

ReviewJournal of gastroenterology2010

Autoimmune pancreatitis: the clinicopathological characteristics of the subtype with granulocytic epithelial lesions.

Günter Klöppel, Sönke Detlefsen, Suresh T Chari, Daniel S Longnecker, Giuseppe Zamboni

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Review
  4. Role of endoscopic ultrasound in diagnosis and management of autoimmune pancreatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Review
  5. Article
  6. Review
  7. A Transient Treatable Tumor of the Pancreas.Digestive diseases and sciences · 2022
    Article
  8. Review
  9. Article
  10. Steroid Therapy and Steroid Response in Autoimmune Pancreatitis.International journal of molecular sciences · 2019
    Review
  11. Review
  12. The clinical utility of immunoglobulin G4 in the evaluation of autoimmune pancreatitis and pancreatic adenocarcinoma.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2018
    Article
  13. Article
  14. Article
  15. Article
  16. Potential role of Th17 cells in the pathogenesis of type 2 autoimmune pancreatitis.Virchows Archiv : an international journal of pathology · 2015
    Article
  17. Article
  18. Review
  19. IgG4-Seronegative Autoimmune Pancreatitis and Sclerosing Cholangitis.Case reports in gastrointestinal medicine · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Günter KlöppelDepartment of Pathology, Technical University of Munich, Ismaninger-Str. 22, 81675 Munich, Germany. guenter.kloeppel@alumni.uni-kiel.de
Sönke Detlefsen
Suresh T Chari
Daniel S Longnecker
Giuseppe Zamboni

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune pancreatitis (AIP) has been established as a distinct form of chronic pancreatitis that is distinguishable from other types such as alcoholic, hereditary or obstructive chronic pancreatitis. AIP seems to be a global disease, since it has been reported in many different countries, especially from Japan, USA and Europe (Germany, Italy, United Kingdom). Typical histopathological findings in the pancreas in AIP include a periductal lymphoplasmacytic infiltration with fibrosis, causing narrowing of the involved ducts. The typical clinical features include presentation with obstructive jaundice/pancreatic mass and a dramatic response to steroids. However, while the reports from Japan describe uniform changes called lymphoplasmacytic sclerosing pancreatitis (LPSP) in the pancreas from AIP patients, the reports from Europe and USA distinguish two histopathologic patterns in AIP patients: one with the characteristics of LPSP and another with slightly different histological features, called idiopathic duct centric pancreatitis (IDCP) or AIP with granulocytic epithelial lesions (GELs). This article reviews the evidence that GEL-positive AIP or IDCP is a second type of AIP, distinct from LPSP, in regard to pancreatic pathology, immunology and epidemiology.

Indexed as

AnimalsAutoimmune DiseasesFibrosarcomaGranulocytesHumansPancreasPancreatitis, Chronic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.