ArticleCell and tissue research1991
Parvalbumin-immunoreactive structures in the hippocampus of the human adult.
Article in Cell and tissue research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 95 citations in OpenAlex.
- Hippocampal architecture viewed through the eyes of methodological development.Anatomical science international · 2025Review
- Absolute Number of Three Populations of Interneurons and All GABAergic Synapses in the Human Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- STForte: tissue context-specific encoding and consistency-aware spatial imputation for spatially resolved transcriptomics.Briefings in bioinformatics · 2025Article
- NECAB1-3, parvalbumin, calbindin, and calretinin in the hippocampus of the European mole.Frontiers in neuroanatomy · 2024Article
- Differential expression of mMolecular neurobiology · 2023Article
- Proportional loss of parvalbumin-immunoreactive synaptic boutons and granule cells from the hippocampus of sea lions with temporal lobe epilepsy.The Journal of comparative neurology · 2019Article
- Cytoarchitectonic Areas of theFrontiers in neuroanatomy · 2019Article
- Synaptic Reorganization of the Perisomatic Inhibitory Network in Hippocampi of Temporal Lobe Epileptic Patients.BioMed research international · 2017Review
- Article
- Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience.BMC medicine · 2012Article
- Characterization of neurons in the CA2 subfield of the adult rat hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
- Morphology and synaptic input of substance P receptor-immunoreactive interneurons in control and epileptic human hippocampus.Neuroscience · 2007Article
- Contingent vulnerability of entorhinal parvalbumin-containing neurons in Alzheimer's disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1996Article
- A golgi study of cell types in the dentate gyrus of the adult human brain.Cellular and molecular neurobiology · 1995Article
- A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads.Acta neuropathologica · 1994Article
- Calcium-binding proteins: selective markers of nerve cells.Cell and tissue research · 1993Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parvalbumin-immunoreactive structures in the fascia dentata and Ammon's horn of the adult human brain were studied using the avidin-biotin-peroxidase technique. Thin fibres (probably axons) were found to form dense networks throughout the cellular layers. Parvalbumin immunoreactivity is observed in even distal portions of nerve cell processes. The excellent quality of the immunoreaction renders the distinction of a large number of possible neuronal types. All parvalbumin-immunoreactive neurons belong to the class of non-granule cells in the fascia dentata and non-pyramidal neurons in Ammon's horn. The fascia dentata harbours four types of neurons in the molecular layer, one type within the granule cell layer and four types in the plexiform layer. The frequently described basket cells are contained in the group of immunoreactive non-granule cells in the plexiform layer. In field CA4 two neuronal types can be distinguished. Field CA3 reveals a slender cell type in the stratum radiatum, three types in the pyramidal cell layer and three types in the stratum oriens. In field CA2 three neuronal types can be differentiated in the stratum pyramidale. The extended field CA1 is endowed with two types of nerve cells within the stratum moleculare, two types in the stratum radiatum, five neuronal types in the stratum pyramidale, and one spindle-shaped type in the stratum oriens. The morphological features of parvalbumin-immunoreactive neuronal types in the adult human brain are compared with those found in Golgi-studies of mostly young animals or in labelling experiments. This study serves as a basis for further analyzes involving specific diseases such as Alzheimer's disease or epilepsy, where it needs to be clarified to which extent certain neuronal types are afflicted.
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