ReviewThe Journal of physiology2010
Changes in the force-velocity relationship of fatigued muscle: implications for power production and possible causes.
Review in The Journal of physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Hormonal and neuromuscular responses to mechanical vibration applied to upper extremity muscles.PloS one · 2014Trial
- Dose-dependent effects and mechanisms of exercise-like stimulation on cardiac injury and contractile function: outcomes of the MICRO-ATHLETE study.Basic research in cardiology · 2026Article
- Muscle Weakness and the Irisin-BDNF and Oxidative Stress Axis in the 60-Day Pseudorandomised Controlled AGBRESA Bed Rest Study.Journal of cachexia, sarcopenia and muscle · 2026Article
- Mathematical Comparison of Time-Based and Stroke-Based Fatigue Models in Elite Sprint Cycling: Convergence Analysis and Practical Applications.Scandinavian journal of medicine & science in sports · 2026Article
- Sensitivity of the load-velocity relationship variables to discriminate the level of fatigue induced by multiple sets of the smith-machine squat exercise.BMC sports science, medicine & rehabilitation · 2026Article
- AAV-shDUX4 provides short-term benefits but limited long-term efficacy in a DUX4 mouse model of FSHD.Molecular therapy. Methods & clinical development · 2025Article
- Neuromuscular fatigue reduces force responsiveness when controlling leg external forces.Physiological reports · 2025Article
- A simple on-field fast knee-flexion test to assess acute knee flexor fatigue.European journal of applied physiology · 2025Article
- Microscale velocity-dependent unbinding generates a macroscale performance-efficiency tradeoff in actomyosin systems.Communications biology · 2025Article
- A novel approach to monitoring selective fatigue in female softball athletes: evaluating load-velocity relationship variables and specific performance metrics.Frontiers in physiology · 2025Article
- Linking in vivo muscle dynamics to force-length and force-velocity properties reveals that guinea fowl lateral gastrocnemius operates at shorter than optimal lengths.The Journal of experimental biology · 2024Article
- Feasibility of vertical force-velocity profiles to monitor changes in muscle function following different fatigue protocols.European journal of applied physiology · 2024Article
- Comparison of Neuromuscular Fatigue in Powerlifting Paralympics in Different Training Methods.Sports medicine international open · 2024Article
- LinkingbioRxiv : the preprint server for biology · 2023Article
- Evaluation of the Training Session in Elite Paralympic Powerlifting Athletes Based on Biomechanical and Thermal Indicators.Sports (Basel, Switzerland) · 2023Article
- Whole Body Vibration Training Improves Maximal Strength of the Knee Extensors, Time-to-Exhaustion and Attenuates Neuromuscular Fatigue.Sports (Basel, Switzerland) · 2023Article
- Comparison of prolonged low-frequency force depression assessed using isometric torque and isotonic power following a dynamic fatiguing task.European journal of applied physiology · 2022Article
- Analysis of Biomechanical and Biochemical Markers of RatNanomaterials (Basel, Switzerland) · 2022Article
- Molecular Events of the Crossbridge Cycle Reflected in the Force-Velocity Relationship of Activated Muscle.Frontiers in physiology · 2022Review
- Maximal muscular power: lessons from sprint cycling.Sports medicine - open · 2021Review
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
Slowing of the contractile properties of skeletal muscle is one of the characteristic features of fatigue. First studied as a slowing of relaxation from an isometric contraction, it has become apparent that this slowing is indicative of functional changes in muscle responsible for a major loss of power with all its functional repercussions. There are three factors contributing to the loss of power in mammalian muscle at physiological temperatures, a decrease in isometric force, which mainly indicates a reduction in the number of active cross bridges, a slowing of the maximum velocity of unloaded shortening and an increased curvature of the force-velocity relationship. This latter change is a major cause of loss of power but is poorly understood. It is probably associated with an increase in the proportion of cross bridges in the low force state but there are no clear candidates for the metabolic changes that are responsible for this shift in cross bridge states. The possibility is discussed that the reduction in activating calcium that occurs with metabolically depleted muscle, alters the distribution of cross bridge states, affecting both shortening velocity and curvature.
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