ArticleJournal of neurology, neurosurgery, and psychiatry2011
Nosocomial transmission of sporadic Creutzfeldt-Jakob disease: results from a risk-based assessment of surgical interventions.
Article in Journal of neurology, neurosurgery, and psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Interventions to reduce the risk of surgically transmitted Creutzfeldt-Jakob disease: a cost-effective modelling review.Health technology assessment (Winchester, England) · 2020Pooled it
- Risk of transmission of sporadic Creutzfeldt-Jakob disease by surgical procedures: systematic reviews and quality of evidence.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2017Pooled it
- Quality indicators for colonoscopy procedures: a prospective multicentre method for endoscopy units.PloS one · 2012Trial
- Article
- Rapid and sensitive determination of residual prion infectivity from prion-decontaminated surfaces.mSphere · 2024Article
- The role of environmental factors on sporadic Creutzfeldt-Jakob disease mortality: evidence from an age-period-cohort analysis.European journal of epidemiology · 2023Article
- Article
- Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease.Science translational medicine · 2017Article
- Sporadic and Infectious Human Prion Diseases.Cold Spring Harbor perspectives in medicine · 2017Review
- Prions: Beyond a Single Protein.Clinical microbiology reviews · 2016Review
- Drivers: A Biologically Contextualized, Cross-Inferential View of the Epidemiology of Neurodegenerative Disorders.Journal of Alzheimer's disease : JAD · 2016Article
- Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features.Frontiers in aging neuroscience · 2016Article
- Creutzfeldt-Jakob disease mortality in Canada, 1998 to 2013.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2015Article
- Creutzfeldt-Jakob disease: The search for definitive diagnostic tests continues.Neurology. Clinical practice · 2015Article
- Towards an age-dependent transmission model of acquired and sporadic Creutzfeldt-Jakob disease.PloS one · 2014Article
- Late-in-life surgery associated with Creutzfeldt-Jakob disease: a methodological outline for evidence-based guidance.Emerging themes in epidemiology · 2013Article
- Article
- A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay.The Journal of general virology · 2011Article
- Molecular pathology of human prion disease.Acta neuropathologica · 2011Review
- Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases.PloS one · 2011Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesEvidence of surgical transmission of sporadic Creutzfeldt-Jakob disease (sCJD) remains debatable in part due to misclassification of exposure levels. In a registry-based case-control study, the authors applied a risk-based classification of surgical interventions to determine the association between a history of surgery and sCJD.
designCase-control study, allowing for detailed analysis according to time since exposure.
settingNational populations of Denmark and Sweden.
participantsFrom national registries of Denmark and Sweden, the authors included 167 definite and probable sCJD cases with onset during the period 1987-2003, 835 age-, sex- and residence-matched controls and 2224 unmatched. Surgical procedures were categorised by anatomical structure and presumed risk of transmission level. The authors used logistic regression to determine the odds ratio (OR) for sCJD by surgical interventions in specified time-windows before disease-onset.
resultsFrom comparisons with matched controls, procedures involving retina and optic nerve were associated with an increased risk at a latency of ≥1 year OR (95% CI) 5.53 (1.08 to 28.0). At latencies of 10 to 19 years, interventions on peripheral nerves 4.41 (1.17 to 16.6) and skeletal muscle 1.58 (1.01 to 2.48) were directly associated. Interventions on blood vessels 4.54 (1.01 to 20.0), peritoneum 2.38 (1.14 to 4.96) and skeletal muscle 2.04 (1.06 to 3.92), interventions conducted by vaginal approach 2.26 (1.14 to 4.47) and a pooled category of lower-risk procedures 2.81 (1.62 to 4.88) had an increased risk after ≥20 years. Similar results were found when comparing with unmatched controls.
interpretationThis observation is in concordance with animal models of prion neuroinvasion and is likely to represent a causal relation of surgery with a non-negligible proportion of sCJD cases.
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