Trial reportExperimental and clinical psychopharmacology2010
Prolonged duration of craving, mood, and autonomic responses elicited by cues and imagery in smokers: Effects of tobacco deprivation and sex.
Trial report in Experimental and clinical psychopharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Differences in Magnitude of Cue Reactivity Across Durations of Smoking History: A Meta-analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Pooled it
- Branded packaging raises likelihood of cigarette purchasing in an experimental retail setting by increasing craving.Drug and alcohol dependence · 2026Trial
- Effects of electronic cigarette e-liquid flavouring on cigarette craving.Tobacco control · 2023Trial
- Both active and sham low-frequency rTMS single sessions over the right DLPFC decrease cue-induced cravings among pathological gamblers seeking treatment: A randomized, double-blind, sham-controlled crossover trial.Journal of behavioral addictions · 2018Trial
- Second Generation Electronic Nicotine Delivery System Vape Pen Exposure Generalizes as a Smoking Cue.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018Trial
- Trial
- Exposure to electronic nicotine delivery systems (ENDS) visual imagery increases smoking urge and desire.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2016Trial
- Passive exposure to electronic cigarette (e-cigarette) use increases desire for combustible and e-cigarettes in young adult smokers.Tobacco control · 2015Trial
- Transdermal nicotine during cue reactivity in adult smokers with and without anxiety disorders.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2012Trial
- A comprehensive analysis of craving in smoking cue-exposure research: Differential associations across racial identity and sex.Journal of psychopathology and clinical science · 2025Article
- N-oleoyl alanine attenuates nicotine reward and spontaneous nicotine withdrawal in mice.Drug and alcohol dependence · 2024Article
- Cue Reactivity Effects of Heated Tobacco Product Use in Current, Former, and Never Smokers in the United States.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Article
- A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus.Nature protocols · 2022Article
- Use and perceived usefulness of a just-in-time resonance breathing intervention adjunct for substance use disorder: Contextual and physiological predictors.Frontiers in psychiatry · 2022Article
- Sex Differences in the Association of Cigarette Craving With Insula Structure.The international journal of neuropsychopharmacology · 2021Article
- Effects of Oral pH Changes on Smoking Desire.Balkan medical journal · 2021Article
- Effects of Visual Exposure to IQOS Use on Smoking Urge and Behavior.Tobacco regulatory science · 2021Article
- Heart Rate Variability, Cue-Evoked Ventromedial Prefrontal Cortical Response, and Problem Alcohol Use in Adult Drinkers.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Article
- Exploring the role of the Ser9Gly (rs6280) Dopamine D3 receptor polymorphism in nicotine reinforcement and cue-elicited craving.Scientific reports · 2020Article
- Psychometric properties of the transaddiction craving triggers questionnaire in alcohol use disorder.International journal of methods in psychiatric research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Increases in self-reported craving and changes in autonomic functioning are reliably elicited when smokers are exposed to tobacco-related stimuli compared with neutral stimuli. However, few studies have reported the time course of cue-elicited craving or have directly compared the effectiveness of smoking cues versus imagery to evoke a craving response. In addition to these two issues, we investigated the influence of tobacco deprivation and sex on craving, mood, and autonomic responses. Sixty cigarette smokers (30 men, 30 women) were tested in two counterbalanced sessions, one after overnight tobacco deprivation and one during ad libitum smoking. At each session, participants were exposed to four randomized experimental trials: smoking imagery, neutral imagery, smoking cues, and neutral cues. Tobacco craving and mood were assessed repeatedly and physiological measures were recorded continuously for 30 min after imagery or cue exposure. Compared with neutral trials, smoking cues and smoking imagery reliably increased tobacco craving, negative mood, heart rate, and blood pressure and decreased positive mood ratings. Changes were observed immediately after cue and imagery presentation and remained unchanged for 30 min. Responding was greater in the nondeprived condition, and cues elicited more robust responding than imagery for most measures. Women responded more robustly to smoking cues only in the nondeprived condition, whereas imagery evoked greater responses in men during both conditions. These findings provide new data on the time course, magnitude, and tobacco deprivation effects on elicited craving. Sex differences were dependent on stimulus type and deprivation condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.