ReviewZeitschrift fur Rheumatologie2010
[Ocular involvement in spondyloarthropathies: HLA B27 associated uveitis].
Review in Zeitschrift fur Rheumatologie, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Polymorphisms in the Osteopontin Are Associated with Susceptibility to Ankylosing Spondylitis in a Han Chinese Population.BioMed research international · 2018Article
- Efficacy of golimumab on recurrent uveitis in HLA-B27-positive ankylosing spondylitis.International ophthalmology · 2017Article
- The effect of IL-4 and MTHFR gene variants in ankylosing spondylitis.Zeitschrift fur Rheumatologie · 2015Article
- Genetic analysis of TNFST15 variants in ankylosing spondylitis.International journal of clinical and experimental pathology · 2015Article
- [Rheumatic diseases with primary onset in young adults: spondyloarthritis and connective tissue diseases].Der Internist · 2012Article
- Clinical features of ankylosing spondylitis associated with acute anterior uveitis in Chinese patients.International journal of ophthalmology · 2012Article
- Significant association between insertion/deletion polymorphism of the angiotensin-convertig enzyme gene and ankylosing spondylitis.Molecular vision · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most frequent extraarticular manifestation in spondyloarthropathies (SpA) is eye involvement, which is found in 30%-50% of patients. HLA B27 positive patients in particular--mostly those in the subgroup with ankylosing spondylitis--are affected. Prevalence of uveitis increases with duration of disease. Typical eye involvement is sudden-onset unilateral anterior uveitis (iridocyclitis). Most cases respond well to topical corticosteroids. Frequently relapsing or chronic cases may require oral corticosteroids in addition to classical immunosuppressive drugs and, to an increasing extent, also TNF-alpha inhibitors. In the case of the latter, monoclonal antibodies are preferred over receptor antagonists. Acute anterior uveitis may occur as a minimal variation or initial symptom of SpA. These patients should also be seen by a rheumatologist since undiagnosed SpA may be present in a significant percentage and should be included in therapeutic considerations.
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